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erlec1 endoplasmic reticulum lectin 1 [ Danio rerio (zebrafish) ]

Gene ID: 368331, updated on 28-Oct-2024

Summary

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Official Symbol
erlec1provided by ZNC
Official Full Name
endoplasmic reticulum lectin 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030521-15
See related
Ensembl:ENSDARG00000086309 AllianceGenome:ZFIN:ZDB-GENE-030521-15
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb309; zgc:55819; wu:fi15g10
Summary
Predicted to enable carbohydrate binding activity. Predicted to be involved in retrograde protein transport, ER to cytosol. Predicted to act upstream of or within ERAD pathway. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum lumen. Is expressed in several structures, including anterior axial hypoblast; axial mesoderm; axis; hatching gland; and otic placode. Orthologous to human ERLEC1 (endoplasmic reticulum lectin 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See erlec1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (35750708..35760917, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (35624876..35635085, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene proteasome activator subunit 4a Neighboring gene G protein-coupled receptor 75 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) Neighboring gene mitogen-activated protein kinase kinase kinase 4 Neighboring gene potassium channel, subfamily K, member 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. Fung C, et al. Int J Mol Sci, 2023 Jan 27. PMID 36768797, Free PMC Article
  2. Demonstration of the Coexistence of Duplicated LH Receptors in Teleosts, and Their Origin in Ancestral Actinopterygians. Maugars G, et al. PLoS One, 2015. PMID 26271038, Free PMC Article
  3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ERAD pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
  
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde protein transport, ER to cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum lumen IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
endoplasmic reticulum lectin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199432.1 → NP_955464.1  endoplasmic reticulum lectin 1 precursor

    See identical proteins and their annotated locations for NP_955464.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044498
    UniProtKB/TrEMBL
    Q803G0
    Related
    ENSDARP00000105173.2, ENSDART00000127476.3
    Conserved Domains (2) summary
    pfam07915
    Location:341 → 420
    PRKCSH; Glucosidase II beta subunit-like protein
    cl06793
    Location:413 → 466
    PRKCSH; Glucosidase II beta subunit-like protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    35750708..35760917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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