U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

laptm4b lysosomal protein transmembrane 4 beta [ Danio rerio (zebrafish) ]

Gene ID: 368911, updated on 18-Sep-2024

Summary

Official Symbol
laptm4bprovided by ZNC
Official Full Name
lysosomal protein transmembrane 4 betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030616-616
See related
Ensembl:ENSDARG00000035870 AllianceGenome:ZFIN:ZDB-GENE-030616-616
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fd60g10; zgc:73120; wu:fd60g10; si:zc215i13.7
Summary
Predicted to be located in cell projection; multivesicular body membrane; and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in lysosomal membrane. Is expressed in epiphysis; otic placode; otic vesicle; and retina. Orthologous to human LAPTM4B (lysosomal protein transmembrane 4 beta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See laptm4b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (32864577..32888758, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (33277457..33301638, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488533 Neighboring gene ribosomal protein L30 Neighboring gene metadherin a Neighboring gene ribonucleotide reductase M2 b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in multivesicular body membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lysosomal-associated transmembrane protein 4B
Names
lysosomal associated protein transmembrane 4 beta

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200098.2NP_956392.1  lysosomal-associated transmembrane protein 4B

    See identical proteins and their annotated locations for NP_956392.1

    Status: VALIDATED

    Source sequence(s)
    AL807244, EH440716
    UniProtKB/TrEMBL
    Q6PC39, Q801V1
    Related
    ENSDARP00000052079.3, ENSDART00000052080.4
    Conserved Domains (1) summary
    cl04276
    Location:6225
    Mtp; Golgi 4-transmembrane spanning transporter

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    32864577..32888758 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395056.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    1227..25408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)