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higd1a HIG1 hypoxia inducible domain family, member 1A [ Danio rerio (zebrafish) ]

Gene ID: 373084, updated on 2-Nov-2024

Summary

Official Symbol
higd1aprovided by ZNC
Official Full Name
HIG1 hypoxia inducible domain family, member 1Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030826-15
See related
Ensembl:ENSDARG00000022303 AllianceGenome:ZFIN:ZDB-GENE-030826-15
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hig1; cb659; zgc:77692; wu:fb57h02
Summary
Predicted to be involved in mitochondrial respirasome assembly. Predicted to be located in membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including axis; gill; musculature system; solid lens vesicle; and spleen. Orthologous to human HIGD1A (HIG1 hypoxia inducible domain family member 1A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See higd1a in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2168547..2173749)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (1825741..1830943)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 23 Neighboring gene desmoplakin a Neighboring gene uncharacterized LOC137487662 Neighboring gene coiled-coil domain containing 13 Neighboring gene transmembrane inner ear

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in mitochondrial respirasome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
HIG1 domain family member 1A, mitochondrial
Names
hypoxia induced gene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200100.2NP_956394.1  HIG1 domain family member 1A, mitochondrial

    See identical proteins and their annotated locations for NP_956394.1

    Status: VALIDATED

    Source sequence(s)
    CU929426, EH437255, EH459895
    UniProtKB/TrEMBL
    Q6P5L9, Q7ZZZ4
    Related
    ENSDARP00000033361.7, ENSDART00000029347.8
    Conserved Domains (1) summary
    pfam04588
    Location:2169
    HIG_1_N; Hypoxia induced protein conserved region

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    2168547..2173749
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)