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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009004.2 RefSeqGene
- Range
-
4986..77433
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001382235.1 → NP_001369164.1 potassium voltage-gated channel subfamily KQT member 2 isoform f
Status: REVIEWED
- Source sequence(s)
-
AL121827, AL121829, AL353658, KF456987
- UniProtKB/TrEMBL
- A0A9L9PXL0, Q4VXP6
- Related
- ENSP00000516702.1, ENST00000706989.1
- Conserved Domains (4) summary
-
- pfam00520
Location:92 → 324
- Ion_trans; Ion transport protein
- pfam03520
Location:448 → 669
- KCNQ_channel; KCNQ voltage-gated potassium channel
- pfam11956
Location:786 → 886
- KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
- pfam16642
Location:684 → 774
- KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
-
NM_004518.6 → NP_004509.2 potassium voltage-gated channel subfamily KQT member 2 isoform c
See identical proteins and their annotated locations for NP_004509.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains a distinct 3' UTR and lacks two alternate in-frame exons compared to variant 1, resulting in a shorter isoform (c) compared to isoform a.
- Source sequence(s)
-
AF033348, AF074247, AL121827, AL121829, D82346, DB636326, KF456987, Y15065
- Consensus CDS
-
CCDS13518.1
- UniProtKB/TrEMBL
-
A0A0G2JH35
- Related
- ENSP00000353668.3, ENST00000360480.7
- Conserved Domains (5) summary
-
- pfam00520
Location:119 → 324
- Ion_trans; Ion transport protein
- pfam03520
Location:444 → 629
- KCNQ_channel; KCNQ voltage-gated potassium channel
- pfam07885
Location:240 → 314
- Ion_trans_2; Ion channel
- pfam11956
Location:753 → 840
- KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
- pfam16642
Location:638 → 728
- KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
-
NM_172106.3 → NP_742104.1 potassium voltage-gated channel subfamily KQT member 2 isoform b
See identical proteins and their annotated locations for NP_742104.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in a shorter isoform (b) compared to isoform a.
- Source sequence(s)
-
AF074247, AL121827, AL121829, DB636326, KF456987, Y15065
- Consensus CDS
-
CCDS13519.1
- UniProtKB/TrEMBL
-
A0A0G2JH35
- Related
- ENSP00000486706.1, ENST00000626839.2
- Conserved Domains (5) summary
-
- pfam00520
Location:119 → 324
- Ion_trans; Ion transport protein
- pfam03520
Location:454 → 639
- KCNQ_channel; KCNQ voltage-gated potassium channel
- pfam07885
Location:240 → 314
- Ion_trans_2; Ion channel
- pfam11956
Location:763 → 850
- KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
- pfam16642
Location:648 → 738
- KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
-
NM_172107.4 → NP_742105.1 potassium voltage-gated channel subfamily KQT member 2 isoform a
See identical proteins and their annotated locations for NP_742105.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AF033348, AF074247, AL121827, AL121829, D82346, DB636326, KF456987, Y15065
- Consensus CDS
-
CCDS13520.1
- UniProtKB/Swiss-Prot
- O43526, O43796, O75580, O95845, Q4VXP4, Q4VXR6, Q5VYT8, Q96J59, Q99454
- UniProtKB/TrEMBL
-
A0A0G2JH35
- Related
- ENSP00000352035.2, ENST00000359125.7
- Conserved Domains (5) summary
-
- pfam00520
Location:119 → 324
- Ion_trans; Ion transport protein
- pfam03520
Location:472 → 657
- KCNQ_channel; KCNQ voltage-gated potassium channel
- pfam07885
Location:240 → 314
- Ion_trans_2; Ion channel
- pfam11956
Location:781 → 868
- KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
- pfam16642
Location:666 → 756
- KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
-
NM_172108.5 → NP_742106.1 potassium voltage-gated channel subfamily KQT member 2 isoform d
See identical proteins and their annotated locations for NP_742106.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks two alternate in-frame coding segments compared to variant 1, resulting in a shorter isoform (d) compared to isoform a. The 3' UTR of this variant has not been fully characterized.
- Source sequence(s)
-
AF033348, AF074247, AF110020, AL121827, AL121829, D82346, DB636326, KF456987, Y15065
- Consensus CDS
-
CCDS46629.1
- UniProtKB/TrEMBL
-
A0A0G2JH35
- Related
- ENSP00000339611.4, ENST00000344462.8
- Conserved Domains (5) summary
-
- pfam00520
Location:119 → 324
- Ion_trans; Ion transport protein
- pfam03520
Location:442 → 626
- KCNQ_channel; KCNQ voltage-gated potassium channel
- pfam07885
Location:240 → 314
- Ion_trans_2; Ion channel
- pfam11956
Location:750 → 837
- KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
- pfam16642
Location:635 → 725
- KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
-
NM_172109.3 → NP_742107.1 potassium voltage-gated channel subfamily KQT member 2 isoform e
See identical proteins and their annotated locations for NP_742107.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate splice site in the coding region compared to variant 1, resulting in a frameshift. It encodes isoform e, which has a shorter and distinct C-terminus compared to isoform a.
- Source sequence(s)
-
AL121829, AL353658, D82346, DB636326
- Consensus CDS
-
CCDS13521.1
- UniProtKB/TrEMBL
- B4DEP4, Q53Y30
- Related
- ENSP00000345523.5, ENST00000344425.8
- Conserved Domains (1) summary
-
- pfam00520
Location:92 → 324
- Ion_trans; Ion transport protein