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mgll monoglyceride lipase [ Danio rerio (zebrafish) ]

Gene ID: 378960, updated on 2-Nov-2024

Summary

Official Symbol
mgllprovided by ZNC
Official Full Name
monoglyceride lipaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031006-9
See related
Ensembl:ENSDARG00000036820 AllianceGenome:ZFIN:ZDB-GENE-031006-9
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb909; zgc:56561; wu:fc66g01
Summary
Predicted to enable monoacylglycerol lipase activity. Predicted to be involved in acylglycerol metabolic process. Predicted to be active in membrane. Is expressed in several structures, including EVL; basal plate midbrain region; brain; digestive system; and eye. Orthologous to human MGLL (monoglyceride lipase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See mgll in Genome Data Viewer
Location:
chromosome: 8
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (26292601..26323849)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (26273462..26304665)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 26 member 6 Neighboring gene solute carrier family 26 member 6 Neighboring gene protein kinase, cAMP-dependent, regulatory, type II, alpha A Neighboring gene hyaluronidase 3 Neighboring gene N-alpha-acetyltransferase 80, NatH catalytic subunit

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC56561

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables monoacylglycerol lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables monoacylglycerol lipase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in acylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
monoglyceride lipase
NP_956591.1
XP_068078991.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200297.2NP_956591.1  monoglyceride lipase

    See identical proteins and their annotated locations for NP_956591.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049487
    UniProtKB/TrEMBL
    Q6TGX4, Q7ZWC2
    Related
    ENSDARP00000053462.2, ENSDART00000053463.4
    Conserved Domains (2) summary
    pfam12146
    Location:39275
    Hydrolase_4; Serine aminopeptidase, S33
    cl21494
    Location:22294
    Abhydrolase; alpha/beta hydrolases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    26292601..26323849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068222890.1XP_068078991.1  monoglyceride lipase isoform X1