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rab11al RAB11a, member RAS oncogene family, like [ Danio rerio (zebrafish) ]

Gene ID: 386994, updated on 12-Sep-2024

Summary

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Official Symbol
rab11alprovided by ZNC
Official Full Name
RAB11a, member RAS oncogene family, likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031118-188
See related
Ensembl:ENSDARG00000014340 AllianceGenome:ZFIN:ZDB-GENE-031118-188
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc54g10; zgc:63565; wu:fc54g10
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in exocytosis. Predicted to be active in recycling endosome. Is expressed in several structures, including EVL; hatching gland; integument; periderm; and polster. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See rab11al in Genome Data Viewer
Location:
chromosome: 16
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (46725087..46741772)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (46758371..46775056)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Neighboring gene RAB25, member RAS oncogene family b Neighboring gene mex-3 RNA binding family member A Neighboring gene uncharacterized LOC100535095

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation of Rab-based transgenic lines for in vivo studies of endosome biology in zebrafish. Clark BS, et al. Dev Dyn, 2011 Nov. PMID 21976318, Free PMC Article
  2. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Westlake CJ, et al. Proc Natl Acad Sci U S A, 2011 Feb 15. PMID 21273506, Free PMC Article
  3. The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation. Wei S, et al. Cell Res, 2017 Feb. PMID 27910850, Free PMC Article
  4. Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components. van der Sar AM, et al. Mol Immunol, 2009 Jul. PMID 19409617
  5. Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber. Takamiya M, et al. PLoS One, 2015. PMID 25692557, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in melanosome transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in postsynaptic recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RAB11a, member RAS oncogene family, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200123.1 → NP_956417.1  RAB11a, member RAS oncogene family, like

    See identical proteins and their annotated locations for NP_956417.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055141
    UniProtKB/TrEMBL
    Q7SY35
    Related
    ENSDARP00000016540.6, ENSDART00000008920.8
    Conserved Domains (2) summary
    PLN03110
    Location:1 → 215
    PLN03110; Rab GTPase; Provisional
    cd01868
    Location:9 → 173
    Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    46725087..46741772
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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