baiap2l1a BAR/IMD domain containing adaptor protein 2 like 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: baiap2l1aprovided by ZNC
Official Full Name: BAR/IMD domain containing adaptor protein 2 like 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-031201-1
See related: Ensembl:ENSDARG00000029305 AllianceGenome:ZFIN:ZDB-GENE-031201-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb1023; baiap2l1; zgc:85624
Summary: Predicted to be involved in actin crosslink formation; actin filament bundle assembly; and positive regulation of actin filament polymerization. Predicted to act upstream of or within plasma membrane organization. Predicted to be active in cytosol and nucleoplasm. Is expressed in several structures, including EVL; central nervous system; digestive system; periderm; and pronephric duct. Orthologous to human BAIAP2L1 (BAR/IMD domain containing adaptor protein 2 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 12

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (17815943..17863301, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (17694069..17741451, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in actin crosslink formation	IBA Inferred from Biological aspect of Ancestor more info
involved_in actin filament bundle assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within plasma membrane organization	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1a

Names: BAI1-associated protein 2-like 1; BAI1-associated protein 2-like 1a; insulin receptor tyrosine kinase substrate homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198922.1 → NP_944604.1 brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1a

See identical proteins and their annotated locations for NP_944604.1

Status: PROVISIONAL

Source sequence(s)

BC050238

UniProtKB/TrEMBL

Q7ZWI3

Conserved Domains (2) summary

cd11913
Location:330 → 387

SH3_BAIAP2L1; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 1, also called Insulin Receptor Tyrosine Kinase Substrate (IRTKS)

cl12013
Location:6 → 230

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007123.7 Reference GRCz11 Primary Assembly

Range

17815943..17863301 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009306593.4 → XP_009304868.1 brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1a isoform X1

UniProtKB/TrEMBL

A0A8M3AYA0, E7F8C7

Related

ENSDARP00000042005.7, ENSDART00000042006.9

Conserved Domains (2) summary

cd11913
Location:330 → 387

SH3_BAIAP2L1; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 1, also called Insulin Receptor Tyrosine Kinase Substrate (IRTKS)

cl12013
Location:6 → 230

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature