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imp3 IMP U3 small nucleolar ribonucleoprotein 3 [ Danio rerio (zebrafish) ]

Gene ID: 393237, updated on 2-Nov-2024

Summary

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Official Symbol
imp3provided by ZNC
Official Full Name
IMP U3 small nucleolar ribonucleoprotein 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1062
See related
Ensembl:ENSDARG00000115266 AllianceGenome:ZFIN:ZDB-GENE-040426-1062
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56526
Summary
Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to act upstream of or within ribosome biogenesis. Part of Mpp10 complex. Orthologous to human IMP3 (IMP U3 small nucleolar ribonucleoprotein 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See imp3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (9983076..9989947, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (10185256..10192127, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene TSEN15 tRNA splicing endonuclease subunit Neighboring gene zgc:55943 Neighboring gene SEC22 homolog B, vesicle trafficking protein a Neighboring gene solute carrier family 35 member A3b Neighboring gene family with sequence similarity 78 member Ba

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Sas10 controls ribosome biogenesis by stabilizing Mpp10 and delivering the Mpp10-Imp3-Imp4 complex to nucleolus. Zhao S, et al. Nucleic Acids Res, 2019 Apr 8. PMID 30773582, Free PMC Article
  2. Characterization of genetic loss-of-function of Fus in zebrafish. Lebedeva S, et al. RNA Biol, 2017 Jan 2. PMID 27898262, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC56526

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Mpp10 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mpp10 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
U3 small nucleolar ribonucleoprotein protein IMP3
Names
IMP3, U3 small nucleolar ribonucleoprotein, homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291357.1 → NP_001278286.1  U3 small nucleolar ribonucleoprotein protein IMP3

    Status: VALIDATED

    Source sequence(s)
    EH466588, EH493453, EH598772
    UniProtKB/TrEMBL
    A0A2R8QAU3, A0A8M1P6M9
    Related
    ENSDARP00000148639.1, ENSDART00000184369.1
    Conserved Domains (3) summary
    COG0522
    Location:1 → 177
    RpsD; Ribosomal protein S4 or related protein [Translation, ribosomal structure and biogenesis]
    pfam00163
    Location:5 → 55
    Ribosomal_S4; Ribosomal protein S4/S9 N-terminal domain
    pfam01479
    Location:108 → 154
    S4; S4 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    9983076..9989947 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_200267.1: Suppressed sequence

    Description
    NM_200267.1: This RefSeq was permanently suppressed because it was based on a chimeric sequence.
Nucleotide Protein Strain
Heading Accession and Version

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