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rnf175 ring finger protein 175 [ Danio rerio (zebrafish) ]

Gene ID: 393278, updated on 28-Oct-2024

Summary

Official Symbol
rnf175provided by ZNC
Official Full Name
ring finger protein 175provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1104
See related
Ensembl:ENSDARG00000037647 AllianceGenome:ZFIN:ZDB-GENE-040426-1104
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56665
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ERAD pathway. Predicted to be located in membrane. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Orthologous to human RNF175 (ring finger protein 175). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See rnf175 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (10037444..10048514, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (9353333..9364387, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene eosinophil lineage-specific marker Neighboring gene tripartite motif containing 2b Neighboring gene fibrinogen beta chain Neighboring gene fibrinogen alpha chain

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC56665

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RING finger protein 175
Names
DKEYP-75B4.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328343.1NP_001315272.1  RING finger protein 175 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    BX548256
    UniProtKB/TrEMBL
    A0A8M1P4N4, F1QUH4
    Related
    ENSDARP00000108386.2, ENSDART00000125358.3
    Conserved Domains (1) summary
    pfam13639
    Location:210261
    zf-RING_2; Ring finger domain
  2. NM_200308.3NP_956602.2  RING finger protein 175 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon, resulting in the use of a downstream translational start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    BX548256
    UniProtKB/TrEMBL
    A0A8M1PH01, B8A5M0
    Related
    ENSDARP00000054834.5, ENSDART00000054835.7
    Conserved Domains (1) summary
    pfam13639
    Location:198249
    zf-RING_2; Ring finger domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    10037444..10048514 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466728.2XP_021322403.1  RING finger protein 175 isoform X1

    UniProtKB/TrEMBL
    A0A8M9P7Z3
    Conserved Domains (1) summary
    cl17238
    Location:210239
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain