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med18 mediator of RNA polymerase II transcription, subunit 18 homolog (yeast) [ Danio rerio (zebrafish) ]

Gene ID: 393306, updated on 2-Nov-2024

Summary

Official Symbol
med18provided by ZNC
Official Full Name
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1276
See related
Ensembl:ENSDARG00000041237 AllianceGenome:ZFIN:ZDB-GENE-040426-1276
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:63855
Summary
Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of transcription initiation by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Orthologous to human MED18 (mediator complex subunit 18). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See med18 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (7376471..7379275, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (7459125..7461929, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene forkhead box O6 a Neighboring gene uncharacterized LOC137487874 Neighboring gene ATG5 autophagy related 5 homolog (S. cerevisiae) Neighboring gene PR domain containing 1a, with ZNF domain

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC63855

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of core mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mediator complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mediator of RNA polymerase II transcription subunit 18
Names
mediator complex subunit 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200335.1NP_956629.1  mediator of RNA polymerase II transcription subunit 18

    See identical proteins and their annotated locations for NP_956629.1

    Status: PROVISIONAL

    Source sequence(s)
    BC053113
    UniProtKB/Swiss-Prot
    Q7T3H7
    Related
    ENSDARP00000060446.3, ENSDART00000060447.4
    Conserved Domains (1) summary
    pfam09637
    Location:19207
    Med18; Med18 protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    7376471..7379275 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)