psmd3 proteasome 26S subunit, non-ATPase 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmd3provided by ZNC
Official Full Name: proteasome 26S subunit, non-ATPase 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1444
See related: Ensembl:ENSDARG00000018124 AllianceGenome:ZFIN:ZDB-GENE-040426-1444
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:65867; zgc:77369
Summary: Predicted to enable enzyme regulator activity. Acts upstream of or within brain development; larval locomotory behavior; and otic vesicle development. Predicted to be part of proteasome regulatory particle, lid subcomplex. Orthologous to human PSMD3 (proteasome 26S subunit, non-ATPase 3). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (48049247..48059334)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (48388970..48399057)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

G46291 (e-PCR)
- UniSTS:107093

fj09f08.y1 (e-PCR)
- UniSTS:198492

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables enzyme regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within brain development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within central nervous system development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within larval locomotory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within otic vesicle development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of protein catabolic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 3

Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200572.1 → NP_956866.1 26S proteasome non-ATPase regulatory subunit 3

See identical proteins and their annotated locations for NP_956866.1

Status: PROVISIONAL

Source sequence(s)

BC056598

UniProtKB/TrEMBL

Q6NYV1, Q6PHD1

Related

ENSDARP00000025779.8, ENSDART00000027158.10

Conserved Domains (2) summary

pfam01399
Location:327 → 431

PCI; PCI domain

pfam08375
Location:434 → 492

Rpn3_C; Proteasome regulatory subunit C-terminal