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rps7 ribosomal protein S7 [ Danio rerio (zebrafish) ]

Gene ID: 393725, updated on 28-Oct-2024

Summary

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Official Symbol
rps7provided by ZNC
Official Full Name
ribosomal protein S7provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1718
See related
Ensembl:ENSDARG00000042566 AllianceGenome:ZFIN:ZDB-GENE-040426-1718
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73216
Summary
Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development; hemopoiesis; and regulation of cell cycle. Predicted to be located in several cellular components, including centrosome; nucleus; and ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 8. Orthologous to human RPS7 (ribosomal protein S7). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See rps7 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (30372352..30377169, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (30469473..30474290, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488661 Neighboring gene uncharacterized LOC137488588 Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene allantoicase Neighboring gene ribonuclease H1 Neighboring gene myelin transcription factor 1-like, a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Ribosomal protein mutations induce autophagy through S6 kinase inhibition of the insulin pathway. Heijnen HF, et al. PLoS Genet, 2014. PMID 24875531, Free PMC Article
  2. A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization. Pereboom TC, et al. Blood, 2011 Nov 17. PMID 21921046
  3. Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations. MacInnes AW, et al. Proc Natl Acad Sci U S A, 2008 Jul 29. PMID 18641120, Free PMC Article
  4. Many ribosomal protein genes are cancer genes in zebrafish. Amsterdam A, et al. PLoS Biol, 2004 May. PMID 15138505, Free PMC Article
  5. Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafish. Duan J, et al. Int J Biochem Cell Biol, 2011 Aug. PMID 21550419

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC73216

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chordate embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within hemopoiesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein eS7
Names
40S ribosomal protein S7
NP_957046.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200752.1 → NP_957046.1  small ribosomal subunit protein eS7

    See identical proteins and their annotated locations for NP_957046.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059562
    UniProtKB/Swiss-Prot
    P62084
    Related
    ENSDARP00000109497.2, ENSDART00000126229.4
    Conserved Domains (1) summary
    pfam01251
    Location:14 → 191
    Ribosomal_S7e; Ribosomal protein S7e

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    30372352..30377169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62084.1 GenPept UniProtKB/Swiss-Prot:P62084

Gene LinkOut

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