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eif4e2rs1 eukaryotic translation initiation factor 4E family member 2 related sequence 1 [ Danio rerio (zebrafish) ]

Gene ID: 393732, updated on 2-Nov-2024

Summary

Official Symbol
eif4e2rs1provided by ZNC
Official Full Name
eukaryotic translation initiation factor 4E family member 2 related sequence 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1728
See related
Ensembl:ENSDARG00000015835 AllianceGenome:ZFIN:ZDB-GENE-040426-1728
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
eIF4E2B; zgc:73242
Summary
Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See eif4e2rs1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (44427932..44440737)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (44622528..44635333)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene discs, large homolog 4b (Drosophila) Neighboring gene eph receptor B4b Neighboring gene si:ch1073-228j22.2 Neighboring gene centrobin, centrosomal BRCA2 interacting protein

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC73242

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA 7-methylguanosine cap binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 4F complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 4E family member 2 related sequence 1
Names
eif4E-2B
eukaryotic translation initiation factor 4E class II 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200759.2NP_957053.1  eukaryotic translation initiation factor 4E family member 2 related sequence 1

    See identical proteins and their annotated locations for NP_957053.1

    Status: VALIDATED

    Source sequence(s)
    CABZ01118710, EH485715, FO904893
    UniProtKB/TrEMBL
    Q6PBU4, U3RD49
    Related
    ENSDARP00000132205.1, ENSDART00000160207.3
    Conserved Domains (1) summary
    pfam01652
    Location:52208
    IF4E; Eukaryotic initiation factor 4E

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    44427932..44440737
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017353532.3XP_017209021.1  eukaryotic translation initiation factor 4E family member 2 related sequence 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M6YXN8