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tppp3 tubulin polymerization-promoting protein family member 3 [ Danio rerio (zebrafish) ]

Gene ID: 393825, updated on 2-Nov-2024

Summary

Official Symbol
tppp3provided by ZNC
Official Full Name
tubulin polymerization-promoting protein family member 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1909
See related
Ensembl:ENSDARG00000030463 AllianceGenome:ZFIN:ZDB-GENE-040426-1909
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:77934
Summary
Predicted to enable tubulin binding activity. Predicted to be involved in microtubule bundle formation; microtubule polymerization; and positive regulation of protein polymerization. Predicted to colocalize with microtubule. Is expressed in Kupffer's vesicle; central nervous system; forerunner cell group; neural tube; and pronephric duct. Orthologous to human TPPP3 (tubulin polymerization promoting protein family member 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See tppp3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (35229738..35242270)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (34945617..34970793)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene hydroxysteroid (11-beta) dehydrogenase 2 Neighboring gene zinc finger DHHC-type containing 1 Neighboring gene autocrine motility factor receptor b Neighboring gene dipeptidase 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC77934

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in microtubule bundle formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in microtubule polymerization IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within microtubule polymerization IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein polymerization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
colocalizes_with microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
tubulin polymerization-promoting protein family member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201335.2NP_958492.2  tubulin polymerization-promoting protein family member 3

    See identical proteins and their annotated locations for NP_958492.2

    Status: VALIDATED

    Source sequence(s)
    DN858624, EH455616, EH481358
    UniProtKB/TrEMBL
    A0A8N7V052, E7FG48
    Related
    ENSDARP00000117760.1, ENSDART00000144327.3
    Conserved Domains (1) summary
    pfam05517
    Location:13171
    p25-alpha; p25-alpha

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    35229738..35242270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)