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slc15a4 solute carrier family 15 member 4 [ Danio rerio (zebrafish) ]

Gene ID: 393932, updated on 2-Nov-2024

Summary

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Official Symbol
slc15a4provided by ZNC
Official Full Name
solute carrier family 15 member 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1047
See related
Ensembl:ENSDARG00000102612 AllianceGenome:ZFIN:ZDB-GENE-040426-1047
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
bZ1L10.1; zgc:56484; zgc:63767
Summary
Predicted to enable dipeptide transmembrane transporter activity. Predicted to be involved in dipeptide import across plasma membrane. Predicted to act upstream of or within amide transport; protein transport; and transmembrane transport. Predicted to be active in membrane. Is expressed in epidermis; immature eye; nervous system; periderm; and yolk syncytial layer. Orthologous to human SLC15A4 (solute carrier family 15 member 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See slc15a4 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (35809055..35961008, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (36079707..36231660, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496372 Neighboring gene si:dkeyp-14d3.1 Neighboring gene uncharacterized LOC110438828 Neighboring gene glycosyltransferase 1 domain containing 1 Neighboring gene transmembrane protein 132D Neighboring gene major histocompatibility complex class II d8.35a1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Immune gene variation associated with chromosome-scale differences among individual zebrafish genomes. McConnell SC, et al. Sci Rep, 2023 May 13. PMID 37179373, Free PMC Article
  2. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC56484

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables dipeptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dipeptide import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within oligopeptide transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within peptide transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
solute carrier family 15 member 4
Names
bZ1L10.1 (novel peptide transporter)
solute carrier family 15 (oligopeptide transporter), member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320529.1 → NP_001307458.1  solute carrier family 15 member 4

    Status: VALIDATED

    Source sequence(s)
    AL627256, CU693378
    UniProtKB/TrEMBL
    A0A0R4ICA5, A0A8M1P8Q5
    Related
    ENSDARP00000132430.1, ENSDART00000160503.2
    Conserved Domains (1) summary
    cl21472
    Location:158 → 522
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    35809055..35961008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_200957.1: Suppressed sequence

    Description
    NM_200957.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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