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cwc27 CWC27 spliceosome associated cyclophilin [ Danio rerio (zebrafish) ]

Gene ID: 394078, updated on 2-Nov-2024

Summary

Official Symbol
cwc27provided by ZNC
Official Full Name
CWC27 spliceosome associated cyclophilinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1118
See related
Ensembl:ENSDARG00000043727 AllianceGenome:ZFIN:ZDB-GENE-040426-1118
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Sdccag10; zgc:56702
Summary
Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to act upstream of or within protein peptidyl-prolyl isomerization. Predicted to be located in nucleus. Predicted to be part of U2-type precatalytic spliceosome and catalytic step 2 spliceosome. Orthologous to human CWC27 (CWC27 spliceosome associated cyclophilin). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See cwc27 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (11398115..11501424)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (11439873..11543186)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene placenta associated 8, tandem duplicate 1 Neighboring gene SREK1-interacting protein 1 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 6 Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC56702

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein peptidyl-prolyl isomerization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of U2-type precatalytic spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
spliceosome-associated protein CWC27 homolog
Names
CWC27 spliceosome-associated protein homolog
PPIase CWC27
PPIase SDCCAG10
peptidyl-prolyl cis-trans isomerase CWC27 homolog
peptidyl-prolyl cis-trans isomerase SDCCAG10
probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog
NP_957397.1
XP_009303436.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201103.1NP_957397.1  spliceosome-associated protein CWC27 homolog

    See identical proteins and their annotated locations for NP_957397.1

    Status: PROVISIONAL

    Source sequence(s)
    BC049533
    UniProtKB/Swiss-Prot
    Q7ZW86
    Related
    ENSDARP00000064209.3, ENSDART00000064210.4
    Conserved Domains (1) summary
    cd01925
    Location:8178
    cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    11398115..11501424
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009305161.4XP_009303436.1  spliceosome-associated protein CWC27 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M3AWJ7
    Conserved Domains (1) summary
    cd01925
    Location:8178
    cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...