nudt21 nudix hydrolase 21 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nudt21provided by ZNC
Official Full Name: nudix hydrolase 21provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1316
See related: Ensembl:ENSDARG00000003153 AllianceGenome:ZFIN:ZDB-GENE-040426-1316
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cpsf5; zgc:63966
Summary: Predicted to enable identical protein binding activity and mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in several processes, including positive regulation of cell differentiation; protein-containing complex assembly; and regulation of mRNA metabolic process. Predicted to act upstream of or within cell differentiation and mRNA polyadenylation. Predicted to be located in cytoplasm and paraspeckles. Predicted to be part of mRNA cleavage factor complex. Orthologous to human NUDT21 (nudix hydrolase 21). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (22721551..22734963, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (22732485..22745897, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISS Inferred from Sequence or Structural Similarity more info
enables mRNA 3'-UTR AU-rich region binding	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA 3'-UTR AU-rich region binding	ISS Inferred from Sequence or Structural Similarity more info
enables mRNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mRNA 3'-end processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA alternative polyadenylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in mRNA processing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of pro-B cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of stem cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in post-transcriptional regulation of gene expression	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein heterotetramerization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
part_of mRNA cleavage factor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mRNA cleavage factor complex	IEA Inferred from Electronic Annotation more info
part_of mRNA cleavage factor complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in paraspeckles	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cleavage and polyadenylation specificity factor subunit 5

Names: cleavage and polyadenylation specific factor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.