U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tial1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 [ Danio rerio (zebrafish) ]

Gene ID: 394107, updated on 17-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
tial1provided by ZNC
Official Full Name
TIA1 cytotoxic granule-associated RNA binding protein-like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1547
See related
Ensembl:ENSDARG00000009525 AllianceGenome:ZFIN:ZDB-GENE-040426-1547
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66130
Summary
Predicted to enable DNA binding activity and RNA binding activity. Orthologous to human TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tial1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (25472005..25484734, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (25341555..25354303, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene atonal bHLH transcription factor 7 Neighboring gene polycystic kidney disease 2-like 1 Neighboring gene BCL2 associated athanogene 3 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene minichromosome maintenance complex binding protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. England SJ, et al. Front Cell Dev Biol, 2017. PMID 28271061, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC66130

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
nucleolysin TIAR

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201132.1 → NP_957426.1  nucleolysin TIAR

    See identical proteins and their annotated locations for NP_957426.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055501
    UniProtKB/TrEMBL
    A0A8N7V036, Q7SXQ1
    Related
    ENSDARP00000020234.5, ENSDART00000022799.7
    Conserved Domains (4) summary
    cd12616
    Location:9 → 89
    RRM1_TIAR; RNA recognition motif 1 in nucleolysin TIAR and similar proteins
    cd12617
    Location:95 → 174
    RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
    cd12620
    Location:204 → 276
    RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
    TIGR01661
    Location:7 → 270
    ELAV_HUD_SF; ELAV/HuD family splicing factor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    25472005..25484734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156800.5 → XP_005156857.1  nucleolysin TIAR isoform X5

    UniProtKB/TrEMBL
    A0A8M2B2U9
    Conserved Domains (4) summary
    cd12616
    Location:9 → 89
    RRM1_TIAR; RNA recognition motif 1 in nucleolysin TIAR and similar proteins
    cd12617
    Location:95 → 184
    RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
    cd12620
    Location:214 → 286
    RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
    TIGR01661
    Location:7 → 280
    ELAV_HUD_SF; ELAV/HuD family splicing factor

  2. XM_005156799.5 → XP_005156856.1  nucleolysin TIAR isoform X4

    UniProtKB/TrEMBL
    A0A8M2B3J6
    Conserved Domains (4) summary
    COG0724
    Location:7 → 284
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12617
    Location:113 → 192
    RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
    cd12620
    Location:222 → 294
    RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
    cl17169
    Location:9 → 107
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_009307302.4 → XP_009305577.1  nucleolysin TIAR isoform X2

    UniProtKB/TrEMBL
    A0A8M3AZ31
    Conserved Domains (4) summary
    COG0724
    Location:7 → 294
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12617
    Location:113 → 202
    RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
    cd12620
    Location:232 → 304
    RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
    cl17169
    Location:9 → 107
    RRM_SF; RNA recognition motif (RRM) superfamily

  4. XM_005156798.5 → XP_005156855.1  nucleolysin TIAR isoform X3

    UniProtKB/TrEMBL
    A0A8M2B3P8, E9QJJ0
    Related
    ENSDARP00000122887.1, ENSDART00000135321.3
    Conserved Domains (4) summary
    COG0724
    Location:7 → 285
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12617
    Location:114 → 193
    RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
    cd12620
    Location:223 → 295
    RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
    cl17169
    Location:9 → 108
    RRM_SF; RNA recognition motif (RRM) superfamily

  5. XM_005156797.5 → XP_005156854.1  nucleolysin TIAR isoform X1

    UniProtKB/TrEMBL
    A0A8M2B338
    Conserved Domains (4) summary
    COG0724
    Location:7 → 295
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12617
    Location:114 → 203
    RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
    cd12620
    Location:233 → 305
    RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
    cl17169
    Location:9 → 108
    RRM_SF; RNA recognition motif (RRM) superfamily

  6. XM_068212823.1 → XP_068068924.1  nucleolysin TIAR isoform X6

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools