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ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a [ Danio rerio (zebrafish) ]

Gene ID: 399487, updated on 2-Nov-2024

Summary

Official Symbol
ywhaqaprovided by ZNC
Official Full Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040122-5
See related
Ensembl:ENSDARG00000042539 AllianceGenome:ZFIN:ZDB-GENE-040122-5
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ywhaq; ywhaq2
Summary
Predicted to enable monooxygenase activity. Predicted to be involved in protein localization and signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including immature eye; liver; nervous system; otic vesicle; and tail bud. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to several human genes including YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See ywhaqa in Genome Data Viewer
Location:
chromosome: 20
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (29565920..29585336)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29663041..29682457)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene Kruppel like factor 11a Neighboring gene TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B Neighboring gene ADAM metallopeptidase domain 17b Neighboring gene cleavage and polyadenylation specific factor 3

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201513.1NP_958921.1  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a

    See identical proteins and their annotated locations for NP_958921.1

    Status: PROVISIONAL

    Source sequence(s)
    BC048068
    UniProtKB/TrEMBL
    A8KC01, F6NNX8, Q7ZUM0
    Related
    ENSDARP00000062382.3, ENSDART00000062383.4
    Conserved Domains (1) summary
    cl02098
    Location:1233
    14-3-3; 14-3-3 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    29565920..29585336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)