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gtpbp1l GTP binding protein 1, like [ Danio rerio (zebrafish) ]

Gene ID: 402863, updated on 17-Sep-2024

Summary

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Official Symbol
gtpbp1lprovided by ZNC
Official Full Name
GTP binding protein 1, likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041007-2
See related
Ensembl:ENSDARG00000042900 AllianceGenome:ZFIN:ZDB-GENE-041007-2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Is expressed in several structures, including alar plate midbrain region; hatching gland; lens; polster; and solid lens vesicle. Orthologous to human GTPBP1 (GTP binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See gtpbp1l in Genome Data Viewer
Location:
chromosome: 22
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (14836235..14851695)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (14811658..14827142)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 1Ba Neighboring gene uncharacterized LOC110438273 Neighboring gene uncharacterized LOC100537797 Neighboring gene extracellular leucine-rich repeat and fibronectin type III domain containing 2a Neighboring gene MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3'UTR intron-containing NMD targets. Gangras P, et al. PLoS Genet, 2020 Jun. PMID 32502192, Free PMC Article
  2. Identification of target genes downstream of semaphorin6A/PlexinA2 signaling in zebrafish. Emerson SE, et al. Dev Dyn, 2017 Jul. PMID 28440030, Free PMC Article
  3. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GTP binding protein 1, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024811.1 → NP_001019982.1  GTP binding protein 1, like

    See identical proteins and their annotated locations for NP_001019982.1

    Status: VALIDATED

    Source sequence(s)
    BC096803
    UniProtKB/TrEMBL
    Q4V9N2
    Related
    ENSDARP00000105786.2, ENSDART00000122740.3
    Conserved Domains (4) summary
    cd04165
    Location:154 → 378
    GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
    COG5258
    Location:70 → 566
    GTPBP1; GTPase [General function prediction only]
    cd03694
    Location:387 → 473
    GTPBP_II; Domain II of the GTPBP family of GTP binding proteins
    cd03708
    Location:479 → 565
    GTPBP_III; Domain III of the GP-1 family of GTPases

  2. NM_001430984.1 → NP_001417913.1  GTP binding protein 1, like

    Status: VALIDATED

    Source sequence(s)
    BX649639
    Related
    ENSDARP00000155870.1, ENSDART00000180951.1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    14836235..14851695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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