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mul3 mitochondrial E3 ubiquitin protein ligase 3 [ Danio rerio (zebrafish) ]

Gene ID: 402879, updated on 2-Nov-2024

Summary

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Official Symbol
mul3provided by ZNC
Official Full Name
mitochondrial E3 ubiquitin protein ligase 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-240328-1
See related
Ensembl:ENSDARG00000114019 AllianceGenome:ZFIN:ZDB-GENE-240328-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable ligase activity; metal ion binding activity; and ubiquitin-protein transferase activity. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See mul3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (2620617..2624945, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (2778719..2783376, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene corticotropin-releasing factor receptor 2 Neighboring gene myosin, light chain 13 Neighboring gene translation initiation factor eIF2B subunit epsilon-like Neighboring gene SERPINE1 mRNA binding protein 1b Neighboring gene aquaporin 1a (Colton blood group), tandem duplicate 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within organelle organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial ubiquitin ligase activator of nfkb 1-A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    2620617..2624945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171126.5 → XP_005171183.1  mitochondrial ubiquitin ligase activator of nfkb 1-A

    See identical proteins and their annotated locations for XP_005171183.1

    UniProtKB/TrEMBL
    A0A2R8Q6C7, A0A8M2BIE5
    Related
    ENSDARP00000146630.1, ENSDART00000190568.1
    Conserved Domains (1) summary
    pfam12483
    Location:96 → 222
    GIDE; E3 Ubiquitin ligase

  2. XM_005171125.5 → XP_005171182.1  mitochondrial ubiquitin ligase activator of nfkb 1-A

    See identical proteins and their annotated locations for XP_005171182.1

    UniProtKB/TrEMBL
    A0A2R8Q6C7, A0A8M2BIE5
    Conserved Domains (1) summary
    pfam12483
    Location:96 → 222
    GIDE; E3 Ubiquitin ligase

  3. XM_005171127.5 → XP_005171184.1  mitochondrial ubiquitin ligase activator of nfkb 1-A

    See identical proteins and their annotated locations for XP_005171184.1

    UniProtKB/TrEMBL
    A0A2R8Q6C7, A0A8M2BIE5
    Conserved Domains (1) summary
    pfam12483
    Location:96 → 222
    GIDE; E3 Ubiquitin ligase
Nucleotide Protein Strain
Heading Accession and Version

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