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tbpl1 TBP-like 1 [ Danio rerio (zebrafish) ]

Gene ID: 403035, updated on 28-Oct-2024

Summary

Official Symbol
tbpl1provided by ZNC
Official Full Name
TBP-like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040520-2
See related
Ensembl:ENSDARG00000036868 AllianceGenome:ZFIN:ZDB-GENE-040520-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tlf; tlp; trf; trp; trf2; zgc:92340
Summary
Predicted to enable general transcription initiation factor activity. Involved in embryo development and transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Orthologous to human TBPL1 (TATA-box binding protein like 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See tbpl1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (31596529..31605307)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (31669910..31678776)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene EYA transcriptional coactivator and phosphatase 4 Neighboring gene transcription factor 21 Neighboring gene uncharacterized LOC137489136 Neighboring gene solute carrier family 2 member 12 Neighboring gene uncharacterized LOC137489137 Neighboring gene serum/glucocorticoid regulated kinase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC92340

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
TATA box-binding protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205722.1NP_991285.1  TATA box-binding protein-like 1

    See identical proteins and their annotated locations for NP_991285.1

    Status: PROVISIONAL

    Source sequence(s)
    AF503448
    UniProtKB/Swiss-Prot
    Q5U385
    Related
    ENSDARP00000053533.3, ENSDART00000053534.5
    Conserved Domains (2) summary
    PLN00062
    Location:15184
    PLN00062; TATA-box-binding protein; Provisional
    cd04517
    Location:9180
    TLF; TBP-like factors (TLF; also called TLP, TRF, TRP), which are found in most metazoans. TLFs and TBPs have well-conserved core domains; however, they only share about 60% similarity. TLFs, like TBPs, interact with TFIIA and TFIIB, which are part of the ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    31596529..31605307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162305.4XP_005162362.1  TATA box-binding protein-like 1 isoform X1

    See identical proteins and their annotated locations for XP_005162362.1

    UniProtKB/Swiss-Prot
    Q5U385, Q71H63
    Related
    ENSDARP00000134538.1, ENSDART00000160748.2
    Conserved Domains (2) summary
    PLN00062
    Location:15184
    PLN00062; TATA-box-binding protein; Provisional
    cd04517
    Location:9180
    TLF; TBP-like factors (TLF; also called TLP, TRF, TRP), which are found in most metazoans. TLFs and TBPs have well-conserved core domains; however, they only share about 60% similarity. TLFs, like TBPs, interact with TFIIA and TFIIB, which are part of the ...

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395160.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    2657..3350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)