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slco1f1 solute carrier organic anion transporter family, member 1F1 [ Danio rerio (zebrafish) ]

Gene ID: 405853, updated on 17-Sep-2024

Summary

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Official Symbol
slco1f1provided by ZNC
Official Full Name
solute carrier organic anion transporter family, member 1F1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2192
See related
Ensembl:ENSDARG00000102283 AllianceGenome:ZFIN:ZDB-GENE-040426-2192
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:85924
Summary
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to act upstream of or within ion transport and transmembrane transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in kidney and ovary. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder. Orthologous to several human genes including SLCO1A2 (solute carrier organic anion transporter family member 1A2); SLCO1B1 (solute carrier organic anion transporter family member 1B1); and SLCO1B3 (solute carrier organic anion transporter family member 1B3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See slco1f1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (72092462..72105518, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (70576833..70589784, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene protein mono-ADP-ribosyltransferase PARP11 Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene islet amyloid polypeptide Neighboring gene solute carrier organic anion transporter family member 1C1 Neighboring gene solute carrier organic anion transporter family, member 1F4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish Oatp-mediated transport of microcystin congeners. Steiner K, et al. Arch Toxicol, 2016 May. PMID 26055554, Free PMC Article
  2. Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): Phylogenetic analysis and tissue distribution. Popovic M, et al. Comp Biochem Physiol A Mol Integr Physiol, 2010 Mar. PMID 19931635
  3. Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. Muzzio AM, et al. Comp Biochem Physiol A Mol Integr Physiol, 2014 Jan. PMID 24113777, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC85924

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
solute carrier organic anion transporter family, member 1F1
Names
Oatp1f1
solute carrier anion transporting family member 1f1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212917.3 → NP_998082.2  solute carrier organic anion transporter family, member 1F1

    Status: PROVISIONAL

    Source sequence(s)
    LO017820, LO017825
    UniProtKB/TrEMBL
    A0A0R4IBD9, A0A8N1Z406
    Related
    ENSDARP00000132188.1, ENSDART00000167048.2
    Conserved Domains (3) summary
    cd06174
    Location:91 → 336
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:363 → 415
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    pfam03137
    Location:1 → 528
    OATP; Organic Anion Transporter Polypeptide (OATP) family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    72092462..72105518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017354986.3 → XP_017210475.2  solute carrier organic anion transporter family, member 1F1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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