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zgc:56095 zgc:56095 [ Danio rerio (zebrafish) ]

Gene ID: 406286, updated on 2-Nov-2024

Summary

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Official Symbol
zgc:56095provided by ZNC
Official Full Name
zgc:56095provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1948
See related
Ensembl:ENSDARG00000018461 AllianceGenome:ZFIN:ZDB-GENE-040426-1948
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa11g10; fb23g05; zgc:86792; wu:fa11g10; wu:fb23g05
Summary
Predicted to enable ferric iron binding activity and ferrous iron binding activity. Predicted to act upstream of or within intracellular iron ion homeostasis and iron ion transport. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See zgc:56095 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (7741604..7746478)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (7712285..7717159)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene bloodthirsty-related gene family, member 33 Neighboring gene receptor-type tyrosine-protein phosphatase H Neighboring gene RPGR interacting protein 1 Neighboring gene protein tyrosine phosphatase receptor type H Neighboring gene si:dkey-197c15.6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ferric iron binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ferric iron binding IEA
Inferred from Electronic Annotation
more info
  
enables ferrous iron binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within iron ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Ferritin, lower subunit-like; ferritin, lower subunit-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213013.1 → NP_998178.1  Ferritin, lower subunit-like

    See identical proteins and their annotated locations for NP_998178.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045905
    UniProtKB/TrEMBL
    Q7ZVD6
    Related
    ENSDARP00000011510.7, ENSDART00000009687.8
    Conserved Domains (2) summary
    cd01056
    Location:9 → 171
    Euk_Ferritin; eukaryotic ferritins
    pfam00210
    Location:13 → 154
    Ferritin; Ferritin-like domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    7741604..7746478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470123.2 → XP_021325798.1  ferritin, lower subunit-like isoform X1

    UniProtKB/TrEMBL
    A0A8M9PFW3
    Related
    ENSDARP00000151034.1, ENSDART00000193229.1
    Conserved Domains (1) summary
    cd01056
    Location:9 → 171
    Euk_Ferritin; eukaryotic ferritins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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