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hnrnpc heterogeneous nuclear ribonucleoprotein C [ Danio rerio (zebrafish) ]

Gene ID: 406352, updated on 12-Sep-2024

Summary

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Official Symbol
hnrnpcprovided by ZNC
Official Full Name
heterogeneous nuclear ribonucleoprotein Cprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2043
See related
Ensembl:ENSDARG00000053810 AllianceGenome:ZFIN:ZDB-GENE-040426-2043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb57h12; fi16b11; bZ1G18.4; zgc:55701; wu:fb57h12; wu:fi16b11
Summary
Enables mRNA 3'-UTR binding activity. Predicted to be active in nucleus. Orthologous to several human genes including HNRNPC (heterogeneous nuclear ribonucleoprotein C). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See hnrnpc in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (38020782..38034193)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (38039466..38051865)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene apolipoprotein L domain containing 1a Neighboring gene Purkinje cell protein 4 like 1 Neighboring gene DDB1 and CUL4 associated factor 8 Neighboring gene complement component 1, q subcomponent-like 4 like Neighboring gene calsequestrin 1a Neighboring gene si:rp71-1g18.1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characterization of γδ T Cells from Zebrafish Provides Insights into Their Important Role in Adaptive Humoral Immunity. Wan F, et al. Front Immunol, 2016. PMID 28119690, Free PMC Article
  2. Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Vejnar CE, et al. Genome Res, 2019 Jul. PMID 31227602, Free PMC Article
  3. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
heterogeneous nuclear ribonucleoproteins C1/C2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213079.2 → NP_998244.1  heterogeneous nuclear ribonucleoproteins C1/C2

    See identical proteins and their annotated locations for NP_998244.1

    Status: VALIDATED

    Source sequence(s)
    CR376839
    UniProtKB/TrEMBL
    Q4V936, Q803J4
    Related
    ENSDARP00000070385.2, ENSDART00000075905.4
    Conserved Domains (1) summary
    cd12603
    Location:25 → 95
    RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    38020782..38034193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068223588.1 → XP_068079689.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1

  2. XM_068223592.1 → XP_068079693.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X3

  3. XM_068223589.1 → XP_068079690.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X2

  4. XM_068223596.1 → XP_068079697.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X4

  5. XM_021479569.2 → XP_021335244.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X5

    UniProtKB/TrEMBL
    A0A8M9Q728
    Conserved Domains (1) summary
    cd12603
    Location:25 → 95
    RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

  6. XM_021479574.2 → XP_021335249.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X6

    UniProtKB/TrEMBL
    A0A8M9PUR6
    Conserved Domains (1) summary
    cd12603
    Location:25 → 95
    RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

  7. XM_021479568.2 → XP_021335243.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X5

    UniProtKB/TrEMBL
    A0A8M9Q728
    Conserved Domains (1) summary
    cd12603
    Location:25 → 95
    RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

  8. XM_021479572.2 → XP_021335247.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X6

    UniProtKB/TrEMBL
    A0A8M9PUR6
    Conserved Domains (1) summary
    cd12603
    Location:25 → 95
    RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

  9. XM_017358046.3 → XP_017213535.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X7

    UniProtKB/TrEMBL
    A0A8M6Z8V1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394506.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    68030..77059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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