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nup58 nucleoporin 58 [ Danio rerio (zebrafish) ]

Gene ID: 406510, updated on 2-Nov-2024

Summary

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Official Symbol
nup58provided by ZNC
Official Full Name
nucleoporin 58provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2326
See related
Ensembl:ENSDARG00000033965 AllianceGenome:ZFIN:ZDB-GENE-040426-2326
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
nupl1; zgc:85711; wu:fc45d07; wu:fi14f12; wu:fi21d10; zgc:113941
Summary
Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to act upstream of or within mRNA transport; nucleocytoplasmic transport; and protein transport. Part of nuclear pore. Orthologous to human NUP58 (nucleoporin 58). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See nup58 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (25008211..25030189, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (24863037..24885047, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 51 member A Neighboring gene zinc finger DHHC-type palmitoyltransferase 20b Neighboring gene myotubularin related protein 6 Neighboring gene APC membrane recruitment protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development. Strasser MJ, et al. BMC Dev Biol, 2008 May 28. PMID 18507824, Free PMC Article
  2. Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. Rojo-Bartolomé I, et al. PLoS One, 2020. PMID 31999691, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC113941

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear localization sequence binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of nuclear pore IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nucleocytoplasmic transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nuclear pore IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pore IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nucleoporin p58/p45
Names
nucleoporin like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213229.1 → NP_998394.1  nucleoporin p58/p45

    See identical proteins and their annotated locations for NP_998394.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068367
    UniProtKB/TrEMBL
    Q6NUZ9
    Related
    ENSDARP00000022894.7, ENSDART00000019350.9
    Conserved Domains (2) summary
    pfam15967
    Location:64 → 567
    Nucleoporin_FG2; Nucleoporin FG repeated region
    cl02193
    Location:355 → 449
    VirB5_like; VirB5 protein family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    25008211..25030189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162682.5 → XP_005162739.1  nucleoporin p58/p45 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B9L0
    Conserved Domains (2) summary
    pfam15967
    Location:64 → 599
    Nucleoporin_FG2; Nucleoporin FG repeated region
    cl02193
    Location:355 → 449
    VirB5_like; VirB5 protein family

  2. XM_005162685.4 → XP_005162742.1  nucleoporin p58/p45 isoform X5

    UniProtKB/TrEMBL
    A0A8M2B9M4
    Conserved Domains (1) summary
    pfam15967
    Location:64 → 540
    Nucleoporin_FG2; Nucleoporin FG repeated region

  3. XM_005162684.4 → XP_005162741.1  nucleoporin p58/p45 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B9X4
    Conserved Domains (2) summary
    pfam15967
    Location:64 → 568
    Nucleoporin_FG2; Nucleoporin FG repeated region
    cl02193
    Location:356 → 450
    VirB5_like; VirB5 protein family

  4. XM_005162681.4 → XP_005162738.1  nucleoporin p58/p45 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B9R7
    Conserved Domains (2) summary
    pfam15967
    Location:64 → 600
    Nucleoporin_FG2; Nucleoporin FG repeated region
    cl02193
    Location:356 → 450
    VirB5_like; VirB5 protein family

  5. XM_021470124.2 → XP_021325799.1  nucleoporin p58/p45 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PLM6
    Conserved Domains (1) summary
    cl25599
    Location:31 → 477
    Nucleoporin_FG2; Nucleoporin FG repeated region
Nucleotide Protein Strain
Heading Accession and Version

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