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cant1a calcium activated nucleotidase 1a [ Danio rerio (zebrafish) ]

Gene ID: 406558, updated on 18-Sep-2024

Summary

Official Symbol
cant1aprovided by ZNC
Official Full Name
calcium activated nucleotidase 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2441
See related
Ensembl:ENSDARG00000012192 AllianceGenome:ZFIN:ZDB-GENE-040426-2441
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cant1; entpd8; zgc:85724
Summary
Predicted to enable guanosine-diphosphatase activity and uridine-diphosphatase activity. Predicted to be involved in proteoglycan biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7. Orthologous to human CANT1 (calcium activated nucleotidase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See cant1a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (57747716..57765169, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (57677192..57694645, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene galectin 3 binding protein, tandem duplicate 2 Neighboring gene galectin 3 binding protein, tandem duplicate 1 Neighboring gene synaptogyrin 2a Neighboring gene transmembrane channel-like protein 6

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GDP phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables UDP phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside diphosphate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
soluble calcium-activated nucleotidase 1
Names
calcium activated nucleotidase 1
NP_999908.1
XP_005171699.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214743.1NP_999908.1  soluble calcium-activated nucleotidase 1

    See identical proteins and their annotated locations for NP_999908.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068371
    UniProtKB/TrEMBL
    A0A8M1PR26, Q6NUZ5
    Related
    ENSDARP00000025119.6, ENSDART00000013376.9
    Conserved Domains (1) summary
    pfam06079
    Location:116403
    Apyrase; Apyrase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    57747716..57765169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171642.4XP_005171699.1  soluble calcium-activated nucleotidase 1 isoform X1

    See identical proteins and their annotated locations for XP_005171699.1

    UniProtKB/TrEMBL
    A0A8M1PR26, Q6NUZ5
    Conserved Domains (1) summary
    pfam06079
    Location:116403
    Apyrase; Apyrase