krt15 keratin 15 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: krt15provided by ZNC
Official Full Name: keratin 15provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2931
See related: Ensembl:ENSDARG00000036840 AllianceGenome:ZFIN:ZDB-GENE-040426-2931
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55334; wu:fa91c06; wu:fa95d04
Summary: Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Is expressed in cloaca; lateral line system; neuromast mantle cell; pharyngeal arch 3-7 skeleton; and trunk. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive woolly hair 3; corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolytic hyperkeratosis; and palmoplantar keratosis (multiple). Orthologous to several human genes including KRT15 (keratin 15). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (11515778..11518475, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (11532157..11534854, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fa91c06.x1 (e-PCR)
- UniSTS:202550

fk07h01.x1 (e-PCR)
- UniSTS:200542

fk70a05.x1 (e-PCR)
- UniSTS:201435

AI330469 (e-PCR)
- UniSTS:206829

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin, type I cytoskeletal 15

Names: cytokeratin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.