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mfsd14a1 major facilitator superfamily domain containing 14A 1 [ Danio rerio (zebrafish) ]

Gene ID: 406848, updated on 12-Sep-2024

Summary

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Official Symbol
mfsd14a1provided by ZNC
Official Full Name
major facilitator superfamily domain containing 14A 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2935
See related
Ensembl:ENSDARG00000043055 AllianceGenome:ZFIN:ZDB-GENE-040426-2935
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hiat1; hiat1b; zgc:55324; wu:fc64d02; wu:fi04d02; wu:fi11d05
Summary
Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human MFSD14A (major facilitator superfamily domain containing 14A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See mfsd14a1 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (10713711..10735252)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (10684029..10705570)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene hyaluronidase 2b Neighboring gene abhydrolase domain containing 14A Neighboring gene SAS-6 centriolar assembly protein Neighboring gene LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression. Perland E, et al. Open Biol, 2017 Sep. PMID 28878041, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ammonium excretion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MFSD14 family MFS transporter
Names
hippocampus abundant transcript 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213527.2 → NP_998692.2  MFSD14 family MFS transporter

    Status: VALIDATED

    Source sequence(s)
    BX908398, EH497588
    UniProtKB/TrEMBL
    A0A8M1PFD4, Q1LV45
    Related
    ENSDARP00000105716.2, ENSDART00000122349.4
    Conserved Domains (2) summary
    cd06174
    Location:38 → 395
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:40 → 384
    MFS_1; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    10713711..10735252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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