U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cep43 centrosomal protein 43 [ Danio rerio (zebrafish) ]

Gene ID: 415215, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
cep43provided by ZNC
Official Full Name
centrosomal protein 43provided by ZNC
Primary source
ZFIN:ZDB-GENE-090417-1
See related
Ensembl:ENSDARG00000003058 AllianceGenome:ZFIN:ZDB-GENE-090417-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ccr6a; fgfr1op; zgc:86782
Summary
Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cell projection organization and microtubule anchoring. Predicted to be located in cell projection and microtubule organizing center. Predicted to be active in centrosome. Orthologous to human CEP43 (centrosomal protein 43). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cep43 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (30579000..30610172)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (30676082..30707291)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene ribonuclease H1 Neighboring gene myelin transcription factor 1-like, a Neighboring gene chemokine (C-C motif) receptor 6a Neighboring gene acyl-Coenzyme A binding domain containing 3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Defining the origins and evolution of the chemokine/chemokine receptor system. DeVries ME, et al. J Immunol, 2006 Jan 1. PMID 16365434
  2. Time point-based integrative analyses of deep-transcriptome identify four signal pathways in blastemal regeneration of zebrafish lower jaw. Zhang H, et al. Stem Cells, 2015 Mar. PMID 25420467
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microtubule anchoring IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule organizing center IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
centrosomal protein 43
Names
FGFR1 oncogene partner

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002125.1 → NP_001002125.1  centrosomal protein 43

    See identical proteins and their annotated locations for NP_001002125.1

    Status: PROVISIONAL

    Source sequence(s)
    BC071450
    UniProtKB/TrEMBL
    A0A8M1MZX4, Q6IQF6
    Related
    ENSDARP00000011529.7, ENSDART00000010494.10
    Conserved Domains (2) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerization domain
    pfam13499
    Location:161 → 225
    EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    30579000..30610172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468390.2 → XP_021324065.1  centrosomal protein 43 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PSK8
    Conserved Domains (1) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerisation domain

  2. XM_021468391.2 → XP_021324066.1  centrosomal protein 43 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PP81
    Conserved Domains (1) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerisation domain

  3. XM_005160662.5 → XP_005160719.1  centrosomal protein 43 isoform X4

    UniProtKB/TrEMBL
    A0A8M2B7J0
    Conserved Domains (2) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerization domain
    pfam13499
    Location:161 → 225
    EF-hand_7; EF-hand domain pair

  4. XM_068215409.1 → XP_068071510.1  centrosomal protein 43 isoform X5

  5. XM_005160663.5 → XP_005160720.1  centrosomal protein 43 isoform X7

    UniProtKB/TrEMBL
    A0A8M2B7I9
    Conserved Domains (3) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerization domain
    pfam13499
    Location:161 → 225
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:160 → 226
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  6. XM_068215410.1 → XP_068071511.1  centrosomal protein 43 isoform X8

  7. XM_021468393.2 → XP_021324068.1  centrosomal protein 43 isoform X6

    UniProtKB/TrEMBL
    A0A8M9PBN5
    Conserved Domains (1) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerisation domain

  8. XM_017352461.3 → XP_017207950.1  centrosomal protein 43 isoform X10

    UniProtKB/TrEMBL
    A0A8M6YUS2

  9. XM_021468392.2 → XP_021324067.1  centrosomal protein 43 isoform X3

    UniProtKB/TrEMBL
    A0A8M9P2I3
    Conserved Domains (1) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerisation domain

  10. XM_005160664.5 → XP_005160721.1  centrosomal protein 43 isoform X9

    UniProtKB/TrEMBL
    A0A0R4IW74, A0A8M2B7S5
    Related
    ENSDARP00000139051.1, ENSDART00000159485.2
    Conserved Domains (3) summary
    pfam09398
    Location:48 → 128
    FOP_dimer; FOP N terminal dimerization domain
    pfam13499
    Location:161 → 225
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:160 → 226
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  11. XM_068215412.1 → XP_068071513.1  centrosomal protein 43 isoform X11

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools