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hdac11 histone deacetylase 11 [ Danio rerio (zebrafish) ]

Gene ID: 431718, updated on 2-Nov-2024

Summary

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Official Symbol
hdac11provided by ZNC
Official Full Name
histone deacetylase 11provided by ZNC
Primary source
ZFIN:ZDB-GENE-040704-7
See related
Ensembl:ENSDARG00000087573 AllianceGenome:ZFIN:ZDB-GENE-040704-7
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:91942
Summary
Predicted to enable histone deacetylase activity. Predicted to be involved in epigenetic regulation of gene expression. Predicted to be part of histone deacetylase complex. Is expressed in telencephalon. Orthologous to human HDAC11 (histone deacetylase 11). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See hdac11 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (27133491..27199498)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (26896058..26950280)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene IQ motif and Sec7 domain ArfGEF 1b Neighboring gene acyl-CoA dehydrogenase family, member 9 Neighboring gene fibulin 2 Neighboring gene wingless-type MMTV integration site family, member 7Aa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Histone deacetylase 10 structure and molecular function as a polyamine deacetylase. Hai Y, et al. Nat Commun, 2017 May 18. PMID 28516954, Free PMC Article
  2. Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish. Mitra S, et al. iScience, 2018 Sep 28. PMID 30267687, Free PMC Article
  3. Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (HDAC) and lysine acetyltransferase (KAT) genes. Fellous A, et al. Gene, 2019 Apr 5. PMID 30615915
  4. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  5. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables histone deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in epigenetic regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
histone deacetylase 11
NP_001002171.1
XP_021335266.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002171.1 → NP_001002171.1  histone deacetylase 11

    See identical proteins and their annotated locations for NP_001002171.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074052
    UniProtKB/TrEMBL
    Q6GMJ4
    Related
    ENSDARP00000134194.2, ENSDART00000158411.2
    Conserved Domains (1) summary
    cd09993
    Location:46 → 330
    HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    27133491..27199498
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479591.2 → XP_021335266.1  histone deacetylase 11 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QHL6
    Conserved Domains (1) summary
    cd09993
    Location:46 → 339
    HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11
Nucleotide Protein
Heading Accession and Version

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