sntb1 syntrophin, basic 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sntb1provided by ZNC
Official Full Name: syntrophin, basic 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040704-13
See related: Ensembl:ENSDARG00000041729 AllianceGenome:ZFIN:ZDB-GENE-040704-13
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92432
Summary: Predicted to enable structural molecule activity. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of dystrophin-associated glycoprotein complex. Predicted to be active in synapse. Is expressed in epidermis; forebrain; otic vesicle; and pronephric duct. Orthologous to human SNTB1 (syntrophin beta 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (15164763..15263044, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (15274643..15372924, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
part_of dystrophin-associated glycoprotein complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in intracellular anatomical structure	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: beta-1-syntrophin

Names: syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002175.1 → NP_001002175.1 beta-1-syntrophin

See identical proteins and their annotated locations for NP_001002175.1

Status: PROVISIONAL

Source sequence(s)

BC074093

UniProtKB/TrEMBL

B2GRW8, F6NSS1, Q6GMG2

Related

ENSDARP00000105583.1, ENSDART00000125691.3

Conserved Domains (4) summary

smart00233
Location:301 → 410

PH; Pleckstrin homology domain

cd00992
Location:89 → 170

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd01258
Location:220 → 277

PHsplit_syntrophin; Syntrophin Split Pleckstrin homology (PH) domain

pfam00169
Location:301 → 410

PH; PH domain