dnajb6a DnaJ heat shock protein family (Hsp40) member B6a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dnajb6aprovided by ZNC
Official Full Name: DnaJ heat shock protein family (Hsp40) member B6aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-45
See related: Ensembl:ENSDARG00000004680 AllianceGenome:ZFIN:ZDB-GENE-040718-45
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92148; wu:fj44d09
Summary: Predicted to enable chaperone binding activity; protein folding chaperone; and unfolded protein binding activity. Acts upstream of or within locomotory behavior and skeletal muscle tissue development. Predicted to be active in cytoplasm and nucleus. Is expressed in female organism; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 1 and distal spinal muscular atrophy type 5. Orthologous to several human genes including DNAJB6 (DnaJ heat shock protein family (Hsp40) member B6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 2

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (30103305..30118319)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (30119730..30132934)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fj50h11.y1 (e-PCR)
- UniSTS:199485

fj44d09.x1 (e-PCR)
- UniSTS:188569

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables Hsp70 protein binding	IEA Inferred from Electronic Annotation more info
enables protein folding chaperone	IBA Inferred from Biological aspect of Ancestor more info
enables protein-folding chaperone binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chaperone-mediated protein folding	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within chaperone-mediated protein folding	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within locomotory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within skeletal muscle tissue development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: dnaJ homolog subfamily B member 6a

Names: DnaJ (Hsp40) homolog, subfamily B, member 6a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002353.1 → NP_001002353.1 dnaJ homolog subfamily B member 6a

Status: PROVISIONAL

Source sequence(s)

BC075905

UniProtKB/TrEMBL

A0A8M1N0A6, Q6DHR2

Related

ENSDARP00000008680.4, ENSDART00000019417.6

Conserved Domains (1) summary

pfam00226
Location:3 → 66

DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

30103305..30118319

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005163424.5 → XP_005163481.1 dnaJ homolog subfamily B member 6a isoform X1

UniProtKB/TrEMBL

A0A8M1N0A6, Q6DHR2

Related

ENSDARP00000153002.1, ENSDART00000185119.1

Conserved Domains (1) summary

pfam00226
Location:3 → 66

DnaJ; DnaJ domain
XM_005163425.5 → XP_005163482.1 dnaJ homolog subfamily B member 6a isoform X2

UniProtKB/TrEMBL

A0A8M2BAM1

Conserved Domains (1) summary

pfam00226
Location:3 → 66

DnaJ; DnaJ domain
XM_068223731.1 → XP_068079832.1 dnaJ homolog subfamily B member 6a isoform X2