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srprb SRP receptor subunit beta [ Danio rerio (zebrafish) ]

Gene ID: 436845, updated on 28-Oct-2024

Summary

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Official Symbol
srprbprovided by ZNC
Official Full Name
SRP receptor subunit betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-311
See related
Ensembl:ENSDARG00000030949 AllianceGenome:ZFIN:ZDB-GENE-040718-311
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92746; wu:fk57h10; zgc:111820
Summary
Predicted to enable GTP binding activity. Predicted to be involved in protein targeting to ER. Predicted to be located in membrane. Predicted to be part of signal recognition particle receptor complex. Orthologous to human SRPRB (SRP receptor subunit beta). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See srprb in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (2510761..2519610, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (2547189..2556038, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene sialidase 4 Neighboring gene WD repeat domain 53 Neighboring gene cut-like homeobox 1b Neighboring gene SH2B adaptor protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. Zheng W, et al. PLoS One, 2014. PMID 24633177, Free PMC Article
  2. Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish. Yang YJ, et al. Genetics, 2017 Apr. PMID 28193729, Free PMC Article
  3. Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens. Smith LC, et al. Comp Biochem Physiol Part D Genomics Proteomics, 2016 Sep. PMID 27156127, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein targeting to ER IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of signal recognition particle receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
signal recognition particle receptor subunit beta
Names
signal recognition particle receptor, B subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002572.1 → NP_001002572.1  signal recognition particle receptor subunit beta

    See identical proteins and their annotated locations for NP_001002572.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076224
    UniProtKB/TrEMBL
    Q6DGW3
    Related
    ENSDARP00000047012.3, ENSDART00000047013.5
    Conserved Domains (2) summary
    cd04105
    Location:61 → 266
    SR_beta; Signal recognition particle receptor, beta subunit (SR-beta), together with SR-alpha, forms the heterodimeric signal recognition particle (SRP)
    pfam09439
    Location:58 → 237
    SRPRB; Signal recognition particle receptor beta subunit

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    2510761..2519610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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