blvrb biliverdin reductase B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: blvrbprovided by ZNC
Official Full Name: biliverdin reductase Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1516
See related: Ensembl:ENSDARG00000096829 AllianceGenome:ZFIN:ZDB-GENE-030131-1516
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb1064; zgc:91854; wu:fb73f01; CH73-262H23.3
Summary: Is expressed in several structures, including heart; hematopoietic system; kidney; liver; and yolk syncytial layer. Orthologous to human BLVRB (biliverdin reductase B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 18

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (46151536..46160108)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (46153529..46162090)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Suggest that Gata-1 and Nrf2a play differential roles in regulating the heme degradation enzymes hmox1a/bvra/bvrb during an early developmental period of heightened cellular stress
Title: Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fb73f01 (e-PCR), detects polymorphism
- UniSTS:187445

fb73f01.x1 (e-PCR)
- UniSTS:191165

AI545011 (e-PCR)
- UniSTS:206295

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables biliverdin reductase [NAD(P)+] activity	IBA Inferred from Biological aspect of Ancestor more info
enables biliverdin reductase [NAD(P)+] activity	IEA Inferred from Electronic Annotation more info
enables riboflavin reductase (NADPH) activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

Go to the top of the page Help

Preferred Names: flavin reductase (NADPH)

Names: biliverdin reductase B (flavin reductase (NADPH))

NP_001002686.2

EC 1.3.1.24

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.