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meaf6 MYST/Esa1-associated factor 6 [ Danio rerio (zebrafish) ]

Gene ID: 445300, updated on 28-Oct-2024

Summary

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Official Symbol
meaf6provided by ZNC
Official Full Name
MYST/Esa1-associated factor 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-040808-12
See related
Ensembl:ENSDARG00000101216 AllianceGenome:ZFIN:ZDB-GENE-040808-12
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj63g06; wu:fj63g06; zgc:100869
Summary
Predicted to contribute to histone acetyltransferase activity. Predicted to act upstream of or within chromatin organization. Predicted to be located in kinetochore and nucleolus. Predicted to be part of MOZ/MORF histone acetyltransferase complex and NuA4 histone acetyltransferase complex. Orthologous to human MEAF6 (MYST/Esa1 associated factor 6). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See meaf6 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (4024443..4033042)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (4093601..4102216)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene MAP7 domain containing 1b Neighboring gene uncharacterized LOC100149327 Neighboring gene sperm-tail PG-rich repeat containing 1 Neighboring gene bloodthirsty-related gene family, member 23 Neighboring gene bloodthirsty-related gene family, member 24

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes. Can H, et al. BMC Genomics, 2020 Jul 8. PMID 32640983, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to histone H3K14 acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
contributes_to histone H4K12 acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
contributes_to histone H4K5 acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
contributes_to histone H4K8 acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of MOZ/MORF histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
part_of MOZ/MORF histone acetyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NuA4 histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
part_of NuA4 histone acetyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chromatin modification-related protein MEAF6
Names
esa1-associated factor 6 homolog
protein EAF6 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003756.1 → NP_001003756.1  chromatin modification-related protein MEAF6

    See identical proteins and their annotated locations for NP_001003756.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078210
    UniProtKB/Swiss-Prot
    Q6AZD3
    Related
    ENSDARP00000132726.1, ENSDART00000159215.2
    Conserved Domains (1) summary
    pfam09340
    Location:17 → 94
    NuA4; Histone acetyltransferase subunit NuA4

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    4024443..4033042
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005173744.5 → XP_005173801.1  chromatin modification-related protein MEAF6 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IX41, A0A8M2BLF2
    Related
    ENSDARP00000141878.1, ENSDART00000172204.2
    Conserved Domains (1) summary
    pfam09340
    Location:17 → 94
    NuA4; Histone acetyltransferase subunit NuA4
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AZD3.1 GenPept UniProtKB/Swiss-Prot:Q6AZD3

Gene LinkOut

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