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tcf25 transcription factor 25 (basic helix-loop-helix) [ Danio rerio (zebrafish) ]

Gene ID: 445817, updated on 12-Sep-2024

Summary

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Official Symbol
tcf25provided by ZNC
Official Full Name
transcription factor 25 (basic helix-loop-helix)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040905-2
See related
Ensembl:ENSDARG00000040861 AllianceGenome:ZFIN:ZDB-GENE-040905-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101131
Summary
Predicted to be part of RQC complex. Is expressed in lens; mesoderm; notochord; and somite. Orthologous to human TCF25 (transcription factor 25). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See tcf25 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (31117274..31206836)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (31138892..31228504)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene cytochrome b-245, alpha polypeptide Neighboring gene programmed cell death 5 Neighboring gene melanocortin 1 receptor Neighboring gene differentially expressed in FDCP 8 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC101131

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of RQC complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosome quality control complex subunit TCF25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005399.1 → NP_001005399.1  ribosome quality control complex subunit TCF25

    See identical proteins and their annotated locations for NP_001005399.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080235
    UniProtKB/TrEMBL
    Q68EJ4
    Related
    ENSDARP00000059892.7, ENSDART00000059893.7
    Conserved Domains (1) summary
    pfam04910
    Location:217 → 562
    Tcf25; Transcriptional repressor TCF25

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    31117274..31206836
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159180.5 → XP_005159237.1  ribosome quality control complex subunit TCF25 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B5S3
    Related
    ENSDARP00000119333.3, ENSDART00000138403.4
    Conserved Domains (1) summary
    pfam04910
    Location:217 → 557
    Tcf25; Transcriptional repressor TCF25

  2. XM_068214759.1 → XP_068070860.1  ribosome quality control complex subunit TCF25 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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