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kifap3a kinesin-associated protein 3a [ Danio rerio (zebrafish) ]

Gene ID: 447906, updated on 28-Oct-2024

Summary

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Official Symbol
kifap3aprovided by ZNC
Official Full Name
kinesin-associated protein 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040912-74
See related
Ensembl:ENSDARG00000008639 AllianceGenome:ZFIN:ZDB-GENE-040912-74
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101095
Summary
Predicted to enable kinesin binding activity. Predicted to be involved in cilium organization and microtubule-based movement. Predicted to be part of kinesin II complex. Predicted to be active in axoneme and ciliary transition zone. Orthologous to human KIFAP3 (kinesin associated protein 3). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See kifap3a in Genome Data Viewer
Location:
chromosome: 20
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (34420623..34453559, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (34517744..34550680, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene SWT1 RNA endoribonuclease homolog Neighboring gene tRNA methyltransferase 1-like Neighboring gene niban apoptosis regulator 1a Neighboring gene N-terminal Xaa-Pro-Lys N-methyltransferase Neighboring gene golgin, rab6-interacting

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource. Shim H, et al. Nucleic Acids Res, 2016 Nov 16. PMID 27903883, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables kinesin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
  
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in axoneme IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in ciliary transition zone IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of kinesin II complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of kinesin complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
kinesin-associated protein 3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004644.1 → NP_001004644.1  kinesin-associated protein 3a

    See identical proteins and their annotated locations for NP_001004644.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080842
    UniProtKB/TrEMBL
    Q66JN7
    Related
    ENSDARP00000009663.8, ENSDART00000005609.10
    Conserved Domains (2) summary
    cd00020
    Location:538 → 660
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam05804
    Location:13 → 717
    KAP; Kinesin-associated protein (KAP)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    34420623..34453559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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