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s100a1 S100 calcium binding protein A1 [ Danio rerio (zebrafish) ]

Gene ID: 448856, updated on 28-Oct-2024

Summary

Official Symbol
s100a1provided by ZNC
Official Full Name
S100 calcium binding protein A1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040916-1
See related
Ensembl:ENSDARG00000015543 AllianceGenome:ZFIN:ZDB-GENE-040916-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to act upstream of or within regulation of heart contraction. Predicted to be located in mitochondrion and sarcoplasmic reticulum. Predicted to be active in cytoplasm. Is expressed in several structures, including gill; gut; hematopoietic system; olfactory epithelium; and renal system. Orthologous to human S100A1 (S100 calcium binding protein A1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See s100a1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (29385560..29387215, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (29450932..29452592, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene interferon stimulated exonuclease gene 20-like 2 Neighboring gene methyltransferase like 25B Neighboring gene toll-like receptor 18 Neighboring gene si:ch211-113g11.6 Neighboring gene uncharacterized LOC137487914

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of heart contraction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089351.2NP_001082820.1  protein S100-A1

    See identical proteins and their annotated locations for NP_001082820.1

    Status: VALIDATED

    Source sequence(s)
    EH492790, EH575828
    UniProtKB/TrEMBL
    A3KH13, F5HN08
    Related
    ENSDARP00000123790.1, ENSDART00000148787.2
    Conserved Domains (1) summary
    cd05025
    Location:293
    S-100A1; S-100A1: S-100A1 domain found in proteins similar to S100A1. S100A1 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    29385560..29387215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)