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nitr9 novel immune-type receptor 9 [ Danio rerio (zebrafish) ]

Gene ID: 449533, updated on 12-Sep-2024

Summary

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Official Symbol
nitr9provided by ZNC
Official Full Name
novel immune-type receptor 9provided by ZNC
Primary source
ZFIN:ZDB-GENE-041001-6
See related
Ensembl:ENSDARG00000028333 AllianceGenome:ZFIN:ZDB-GENE-041001-6
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
nitr9.1; nitr9_1
Summary
Acts upstream of or within phosphatidylinositol 3-kinase signaling and response to bacterium. Predicted to be integral component of membrane. Is expressed in digestive system; gill; immune system; and myeloid cell. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See nitr9 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (17255707..17309337)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (17051971..17057193)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene protein arginine methyltransferase 3 Neighboring gene si:ch73-266m14.1 Neighboring gene solute carrier family 6 member 5 Neighboring gene novel immune-type receptor 12 Neighboring gene novel immune-type receptor 10a Neighboring gene novel immune-type receptor 11a Neighboring gene lymphocyte antigen 75-like Neighboring gene novel immune-type receptor 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Development and characterization of anti-nitr9 antibodies. Shah RN, et al. Adv Hematol, 2012. PMID 23049557, Free PMC Article
  2. The zebrafish activating immune receptor Nitr9 signals via Dap12. Wei S, et al. Immunogenetics, 2007 Oct. PMID 17891481, Free PMC Article
  3. Differential gene expression following TLR stimulation in rag1-/- mutant zebrafish tissues and morphological descriptions of lymphocyte-like cell populations. Muire PJ, et al. PLoS One, 2017. PMID 28910320, Free PMC Article
  4. Innate immune gene expression in individual zebrafish after Listonella anguillarum inoculation. Rojo I, et al. Fish Shellfish Immunol, 2007 Dec. PMID 17804254
  5. Resolution of the novel immune-type receptor gene cluster in zebrafish. Yoder JA, et al. Proc Natl Acad Sci U S A, 2004 Nov 2. PMID 15496470, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC123078

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within phosphatidylinositol 3-kinase/protein kinase B signal transduction IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within response to bacterium IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
novel immune-type receptor 9
Names
novel immune-type receptor 9.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005576.2 → NP_001005576.2  novel immune-type receptor 9 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    CU179702, CU179757
    UniProtKB/TrEMBL
    Q5YCY6
    Related
    ENSDARP00000130116.2, ENSDART00000163505.2
    Conserved Domains (1) summary
    smart00410
    Location:23 → 96
    IG_like; Immunoglobulin like

  2. NM_001425101.1 → NP_001412030.1  novel immune-type receptor 9 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    CU179702, CU179757
    UniProtKB/TrEMBL
    Q5YCY6
    Related
    ENSDARP00000135070.1, ENSDART00000162169.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    17255707..17309337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068222240.1 → XP_068078341.1  novel immune-type receptor 9 isoform X2

    Related
    ENSDARP00000053356.3, ENSDART00000053357.5

  2. XM_068222236.1 → XP_068078337.1  novel immune-type receptor 9 isoform X1

  3. XM_068222238.1 → XP_068078339.1  novel immune-type receptor 9 isoform X1

  4. XM_068222237.1 → XP_068078338.1  novel immune-type receptor 9 isoform X1

  5. XM_068222239.1 → XP_068078340.1  novel immune-type receptor 9 isoform X1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394681.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    80480..85925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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