tspan7 tetraspanin 7 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tspan7provided by ZNC
Official Full Name: tetraspanin 7provided by ZNC
Primary source: ZFIN:ZDB-GENE-040927-5
See related: Ensembl:ENSDARG00000008407 AllianceGenome:ZFIN:ZDB-GENE-040927-5
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tm4sf2b; tspan7b; zgc:92829; wu:fb53h11
Summary: Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in basal plate midbrain region; nervous system; notochord; and pancreatic bud. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 58. Orthologous to human TSPAN7 (tetraspanin 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (11440705..11493236, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (11411023..11463554, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

AI497464 (e-PCR)
- UniSTS:206340

fb53h11.x1 (e-PCR)
- UniSTS:203316

Z9752 (e-PCR)
- UniSTS:71877

fd08a10.y1 (e-PCR)
- UniSTS:195032

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tetraspanin-7

Names: tetraspanin 7b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001130818.1 → NP_001124290.1 tetraspanin-7

Status: PROVISIONAL

Source sequence(s)

CU459213

UniProtKB/TrEMBL

A0A8M1NIF9, B0VEQ2

Related

ENSDARP00000018179.8, ENSDART00000002691.9

Conserved Domains (2) summary

cd03161
Location:110 → 213

TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

pfam00335
Location:14 → 239

Tetraspannin; Tetraspanin family