gca grancalcin [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gcaprovided by ZNC
Official Full Name: grancalcinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040930-3
See related: Ensembl:ENSDARG00000020187 AllianceGenome:ZFIN:ZDB-GENE-040930-3
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92027
Summary: Predicted to enable calcium ion binding activity. Predicted to be located in cytoplasm. Is expressed in brain; gut; pectoral fin; pronephric duct; and ventricular zone. Orthologous to human GCA (grancalcin). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (13993500..14010528, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (13864063..13881091, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC449543

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005585.1 → NP_001005585.1 uncharacterized protein LOC449543

See identical proteins and their annotated locations for NP_001005585.1

Status: PREDICTED

Source sequence(s)

BC082795

UniProtKB/TrEMBL

Q63ZW0

Related

ENSDARP00000024892.7, ENSDART00000004656.8

Conserved Domains (1) summary

cl08302
Location:82 → 132

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...