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srl sarcalumenin [ Danio rerio (zebrafish) ]

Gene ID: 449670, updated on 28-Oct-2024

Summary

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Official Symbol
srlprovided by ZNC
Official Full Name
sarcalumeninprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061110-91
See related
Ensembl:ENSDARG00000104587 AllianceGenome:ZFIN:ZDB-GENE-061110-91
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6899248; wu:fb94b10; zgc:153844
Summary
Predicted to enable GTP binding activity. Predicted to be involved in endocytosis and endosomal transport. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in adaxial cell; cardiovascular system; musculature system; and somite. Orthologous to human SRL (sarcalumenin). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See srl in Genome Data Viewer
Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (12131701..12186921, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (55900839..55956069, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 100 Neighboring gene adenylate cyclase type 9 pseudogene Neighboring gene transcription factor AP-4 (activating enhancer binding protein 4) Neighboring gene GLIS family zinc finger 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafish. Yao Z, et al. Biol Open, 2013 Jun 15. PMID 23789105, Free PMC Article
  2. Pbx homeodomain proteins direct Myod activity to promote fast-muscle differentiation. Maves L, et al. Development, 2007 Sep. PMID 17699609
  3. CTCF promotes muscle differentiation by modulating the activity of myogenic regulatory factors. Delgado-Olguín P, et al. J Biol Chem, 2011 Apr 8. PMID 21288905, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endosomal transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sarcalumenin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077531.1 → NP_001070999.1  sarcalumenin precursor

    See identical proteins and their annotated locations for NP_001070999.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124749
    UniProtKB/TrEMBL
    A0A8M1NBQ9, A0AUR2
    Related
    ENSDARP00000153671.1, ENSDART00000189553.1
    Conserved Domains (2) summary
    cd09913
    Location:104 → 345
    EHD; Eps15 homology domain (EHD), C-terminal domain
    pfam16880
    Location:56 → 83
    EHD_N; N-terminal EH-domain containing protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    12131701..12186921 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009299804.4 → XP_009298079.1  sarcalumenin isoform X1

    UniProtKB/TrEMBL
    A0A0R4IRI3, A0A8M3B8K9
    Related
    ENSDARP00000138572.1, ENSDART00000165131.3
    Conserved Domains (2) summary
    cd09913
    Location:92 → 333
    EHD; Eps15 homology domain (EHD), C-terminal domain
    pfam16880
    Location:56 → 87
    EHD_N; N-terminal EH-domain containing protein
Nucleotide Protein Strain
Heading Accession and Version

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