U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

arhgap46a Rho GTPase activating protein 46a [ Danio rerio (zebrafish) ]

Gene ID: 492329, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
arhgap46aprovided by ZNC
Official Full Name
Rho GTPase activating protein 46aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-4
See related
Ensembl:ENSDARG00000044874 AllianceGenome:ZFIN:ZDB-GENE-041114-4
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92107; wu:fa99h06; wu:fj78h03
Summary
Predicted to enable GTPase activator activity. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Orthologous to human ARHGAP39 (Rho GTPase activating protein 39). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See arhgap46a in Genome Data Viewer
Location:
chromosome: 11
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24994770..25041804)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24756903..24804188)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 17 homolog A (yeast) Neighboring gene sulfatase 2a Neighboring gene PHD finger protein 20, a Neighboring gene ndrg family member 3a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein LOC492329

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007295.1 → NP_001007296.1  uncharacterized protein LOC492329

    See identical proteins and their annotated locations for NP_001007296.1

    Status: PREDICTED

    Source sequence(s)
    BC085634
    UniProtKB/TrEMBL
    Q5U3A6
    Related
    ENSDARP00000111144.2, ENSDART00000129211.4
    Conserved Domains (2) summary
    cd04389
    Location:872 → 1057
    RhoGAP_KIAA1688; RhoGAP_KIAA1688: GTPase-activator protein (GAP) domain for Rho-like GTPases found in KIAA1688-like proteins; KIAA1688 is a protein of unknown function that contains a RhoGAP domain and a myosin tail homology 4 (MyTH4) domain. Small GTPases cluster into ...
    cl02480
    Location:675 → 859
    MyTH4; MyTH4 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    24994770..25041804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169287.5 → XP_005169344.1  uncharacterized protein LOC492329 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGP1
    Related
    ENSDARP00000134248.2, ENSDART00000167285.2
    Conserved Domains (2) summary
    cd04389
    Location:786 → 971
    RhoGAP_KIAA1688; RhoGAP_KIAA1688: GTPase-activator protein (GAP) domain for Rho-like GTPases found in KIAA1688-like proteins; KIAA1688 is a protein of unknown function that contains a RhoGAP domain and a myosin tail homology 4 (MyTH4) domain. Small GTPases cluster into ...
    cl02480
    Location:589 → 773
    MyTH4; MyTH4 domain

  2. XM_068224156.1 → XP_068080257.1  uncharacterized protein LOC492329 isoform X2

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394821.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    180519..231063
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools