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ralab v-ral simian leukemia viral oncogene homolog Ab (ras related) [ Danio rerio (zebrafish) ]

Gene ID: 492355, updated on 2-Nov-2024

Summary

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Official Symbol
ralabprovided by ZNC
Official Full Name
v-ral simian leukemia viral oncogene homolog Ab (ras related)provided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-195
See related
Ensembl:ENSDARG00000016253 AllianceGenome:ZFIN:ZDB-GENE-041114-195
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb14c06; zgc:92116; wu:fb14c06
Summary
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction and regulation of exocytosis. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human RALA (RAS like proto-oncogene A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See ralab in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (21608352..21618352, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (21950290..21960290, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene inhibin subunit beta Ab Neighboring gene M-phase specific PLK1 interacting protein Neighboring gene zgc:55781 Neighboring gene F-box and leucine-rich repeat protein 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GDP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
v-ral simian leukemia viral oncogene homolog Ab (ras related)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007321.1 → NP_001007322.1  v-ral simian leukemia viral oncogene homolog Ab (ras related)

    See identical proteins and their annotated locations for NP_001007322.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085637
    UniProtKB/TrEMBL
    A0A8M1N3B1, Q5U3A3
    Related
    ENSDARP00000012139.6, ENSDART00000027587.7
    Conserved Domains (2) summary
    smart00010
    Location:11 → 174
    small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
    cd04139
    Location:11 → 173
    RalA_RalB; Ral (Ras-like) family containing highly homologous RalA and RalB

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    21608352..21618352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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