pcdh2ac protocadherin 2 alpha c [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pcdh2acprovided by ZNC
Official Full Name: protocadherin 2 alpha cprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041118-12
See related: Ensembl:ENSDARG00000099783 AllianceGenome:ZFIN:ZDB-GENE-041118-12
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zCNRc; zCNRv9s-1; zCNRv7ss-1
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules and nervous system development. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 14

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (2123123..2163454, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (2204772..2245103, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protocadherin 2 alpha c

Names: cadherin-related neuronal receptor constant; cadherin-related neuronal receptor variable 9 short splicing form 1; cadherin-related neuronal receptor variable 9 short splicing form 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007762.2 → NP_001007763.2 protocadherin 2 alpha c precursor

Status: VALIDATED

Source sequence(s)

CR847851, CT573264

UniProtKB/TrEMBL

Q60I64

Related

ENSDARP00000136655.1, ENSDART00000169653.2

Conserved Domains (4) summary

cd11304
Location:248 → 348

Cadherin_repeat; Cadherin tandem repeat domain

pfam08266
Location:32 → 113

Cadherin_2; Cadherin-like

pfam15974
Location:864 → 981

Cadherin_tail; Cadherin C-terminal cytoplasmic tail, catenin-binding region

pfam16492
Location:692 → 822

Cadherin_C_2; Cadherin cytoplasmic C-terminal