hsdl1 hydroxysteroid dehydrogenase like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hsdl1provided by ZNC
Official Full Name: hydroxysteroid dehydrogenase like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-31
See related: Ensembl:ENSDARG00000041736 AllianceGenome:ZFIN:ZDB-GENE-041212-31
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:103498; si:ch211-172b19.1
Summary: Located in mitochondrion. Is expressed in lens and solid lens vesicle. Orthologous to human HSDL1 (hydroxysteroid dehydrogenase like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (40761726..40766387, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (40864616..40869277, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

characterized the subcellular localization as well as the tissue distribution and performed a screen for putative substrates of HSDL1 enzymes
Title: Human and zebrafish hydroxysteroid dehydrogenase like 1 (HSDL1) proteins are inactive enzymes but conserved among species.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
NOT enables steroid dehydrogenase activity	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: inactive hydroxysteroid dehydrogenase-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008607.1 → NP_001008607.1 inactive hydroxysteroid dehydrogenase-like protein 1

See identical proteins and their annotated locations for NP_001008607.1

Status: PROVISIONAL

Source sequence(s)

BC086821

UniProtKB/Swiss-Prot

A5WWC6, Q5PR56

Related

ENSDARP00000061172.3, ENSDART00000061173.5

Conserved Domains (2) summary

cd05356
Location:67 → 307

17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs

pfam00106
Location:68 → 248

adh_short; short chain dehydrogenase