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crygs2 crystallin, gamma S2 [ Danio rerio (zebrafish) ]

Gene ID: 497123, updated on 2-Nov-2024

Summary

Official Symbol
crygs2provided by ZNC
Official Full Name
crystallin, gamma S2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050126-3
See related
Ensembl:ENSDARG00000041171 AllianceGenome:ZFIN:ZDB-GENE-050126-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
crygs; si:ch211-194d6.4
Summary
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in lens. Human ortholog(s) of this gene implicated in cataract 20 multiple types. Orthologous to human CRYGS (crystallin gamma S). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See crygs2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (27733600..27738110, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (27922854..27927364, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene general transcription factor IIE, polypeptide 1, alpha Neighboring gene leucine carboxyl methyltransferase 2 Neighboring gene TBCC domain containing 1 Neighboring gene RAB5B, member RAS oncogene family Neighboring gene si:rp71-45g20.11

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in visual perception IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
crystallin, gamma S2
Names
gammaSb-crystallin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012262.1NP_001012262.1  crystallin, gamma S2

    See identical proteins and their annotated locations for NP_001012262.1

    Status: PROVISIONAL

    Source sequence(s)
    AY738744
    UniProtKB/TrEMBL
    B3DGE1, F6PAQ4, Q5XTP1
    Related
    ENSDARP00000060346.5, ENSDART00000060347.6
    Conserved Domains (2) summary
    smart00247
    Location:382
    XTALbg; Beta/gamma crystallins
    pfam00030
    Location:91171
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    27733600..27738110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395282.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    401141..405685 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)