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slc30a9 solute carrier family 30 member 9 [ Danio rerio (zebrafish) ]

Gene ID: 497184, updated on 2-Nov-2024

Summary

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Official Symbol
slc30a9provided by ZNC
Official Full Name
solute carrier family 30 member 9provided by ZNC
Primary source
ZFIN:ZDB-GENE-040724-254
See related
Ensembl:ENSDARG00000057272 AllianceGenome:ZFIN:ZDB-GENE-040724-254
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ZnT9; zgc:92098; si:ch211-240l14.4
Summary
Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis; regulation of mitochondrion organization; and zinc ion transport. Predicted to act upstream of or within zinc ion transmembrane transport. Predicted to be located in cytoplasmic vesicle and mitochondrial membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SLC30A9 (solute carrier family 30 member 9). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See slc30a9 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (44804369..44824627)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (44342950..44363318)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene zgc:195212 Neighboring gene glyoxylate reductase/hydroxypyruvate reductase a Neighboring gene translocase of outer mitochondrial membrane 5 homolog (yeast) Neighboring gene glutaredoxin and cysteine rich domain containing 1 a Neighboring gene ATPase phospholipid transporting 8A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model. Beaver LM, et al. J Nutr Biochem, 2017 May. PMID 28268202, Free PMC Article
  2. The involvement of zinc transporters in the zinc accumulation in the Pacific oyster Crassostrea gigas. Kong N, et al. Gene, 2020 Aug 5. PMID 32423892
  3. Zinc transporter expression in zebrafish (Danio rerio) during development. Ho E, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2012 Jan. PMID 21596156, Free PMC Article
  4. The phylogeny of teleost ZIP and ZnT zinc transporters and their tissue specific expression and response to zinc in zebrafish. Feeney GP, et al. Biochim Biophys Acta, 2005 Dec 30. PMID 16500426
  5. Slc39a7/zip7 plays a critical role in development and zinc homeostasis in zebrafish. Yan G, et al. PLoS One, 2012. PMID 22912764, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular zinc ion homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within monoatomic cation transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mitochondrion organization ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within zinc ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in zinc ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within zinc ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within zinc ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in zinc ion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasmic vesicle ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
proton-coupled zinc antiporter SLC30A9, mitochondrial
Names
solute carrier family 30 (zinc transporter), member 9
zinc transporter 9
znT-9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008575.1 → NP_001008575.1  proton-coupled zinc antiporter SLC30A9, mitochondrial

    See identical proteins and their annotated locations for NP_001008575.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086961
    UniProtKB/Swiss-Prot
    Q5PQZ3, Q7SZY6
    Related
    ENSDARP00000074317.5, ENSDART00000079866.7
    Conserved Domains (4) summary
    TIGR00598
    Location:129 → 219
    rad14; DNA repair protein
    TIGR01297
    Location:259 → 525
    CDF; cation diffusion facilitator family transporter
    pfam01545
    Location:256 → 455
    Cation_efflux; Cation efflux family
    pfam12137
    Location:428 → 573
    RapA_C; RNA polymerase recycling family C-terminal

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    44804369..44824627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PQZ3.1 GenPept UniProtKB/Swiss-Prot:Q5PQZ3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.