slc13a5a solute carrier family 13 member 5a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc13a5aprovided by ZNC
Official Full Name: solute carrier family 13 member 5aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4628
See related: Ensembl:ENSDARG00000077691 AllianceGenome:ZFIN:ZDB-GENE-030131-4628
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fd44c11; slc13a5; im:7245905; wu:fd44c11; si:ch211-221p4.4
Summary: Predicted to enable citrate transmembrane transporter activity; sodium:dicarboxylate symporter activity; and succinate transmembrane transporter activity. Acts upstream of or within citrate transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in female organism. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Orthologous to human SLC13A5 (solute carrier family 13 member 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (40053668..40083409, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (40030115..40059896, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables citrate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sodium:dicarboxylate symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables succinate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in citrate transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within citrate transport	IDA Inferred from Direct Assay more info	PubMed
involved_in fumarate transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in oxaloacetate transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sodium ion transport	IEA Inferred from Electronic Annotation more info
involved_in succinate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: solute carrier family 13 member 5a

Names: NaCT; info solute carrier family 13 (sodium-dependent citrate transporter), member 5; info solute carrier family 13 (sodium-dependent citrate transporter), member 5a; sodium-dependent citrate transporter; solute carrier family 13 (sodium-dependent citrate transporter), member 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001142566.1 → NP_001136038.1 solute carrier family 13 member 5a

Status: PROVISIONAL

Source sequence(s)

BX248108

UniProtKB/TrEMBL

A0A8M1NSQ7

Related

ENSDARP00000121887.2, ENSDART00000141160.3

Conserved Domains (2) summary

COG0471
Location:43 → 559

CitT; Di- and tricarboxylate transporter [Carbohydrate transport and metabolism]

cl21473
Location:35 → 566

ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007132.7 Reference GRCz11 Primary Assembly

Range

40053668..40083409 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005161432.5 → XP_005161489.1 solute carrier family 13 member 5a isoform X1

UniProtKB/TrEMBL

A0A2R8QQN0, A0A8M2B8B2

Related

ENSDARP00000157095.1, ENSDART00000191195.1

Conserved Domains (2) summary

COG0471
Location:43 → 563

CitT; Di- and tricarboxylate transporter [Carbohydrate transport and metabolism]

cl21473
Location:35 → 570

ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...